PMID- 20862944 OWN - NLM STAT- MEDLINE DCOM- 20101012 LR - 20100924 IS - 0255-2930 (Print) IS - 0255-2930 (Linking) VI - 30 IP - 7 DP - 2010 Jul TI - [Effects of acupuncture-drug compound anesthesia on perioperative inflammatory factors in patients undergoing cardiac surgery]. PG - 585-8 AB - OBJECTIVE: To explore the effect of acupuncture-drug compound anesthesia on immune function in patients with extracorporeal circulation undergoing cardiac surgery. METHODS: Thirty cases undergoing cardiac surgery which included atrial septal defect neoplasty, ventricular septal defect neoplasty, mitral valve replacement and pulmonary valve coarctotomy were randomly divided into group A and group B, 15 cases in each group. Group A was given general anesthesia plus acupuncture at Neiguan (PC 6), Lieque (LU 7) and Yunmen (LU 2), and group B was given simple general anesthesia. Tumor necrosis factor-alpha (TNF-alpha), interleukin-2 (IL-2) and interleukin-10 (IL-10) levels before and after surgery were compared. RESULTS: The level of TNF-alpha was increased and the levels of IL-2 and IL-10 in the serum were decreased in both groups after extracorporeal circulation for 2 h and 24 h, and the ranges of all changes were more less in group A (all P < 0.05). CONCLUSION: Compared with simple general anesthesia, acupuncture-drug compound anesthesia can improve immune suppression partially in the perioperative periods under the same conditions of controlling anesthesia degree. FAU - Shan, Jiang-Gui AU - Shan JG AD - Department of Cardiothoracic Surgery, Renji Hospital, Medical College of Shanghai Jiaotong University, Shanghai 200127, China. FAU - Xue, Song AU - Xue S FAU - Xu, Gen-Xing AU - Xu GX FAU - Wang, Wei-Jun AU - Wang WJ FAU - Lian, Feng AU - Lian F FAU - Liu, Sha AU - Liu S FAU - Hu, Zhen-Lei AU - Hu ZL FAU - Huang, Ri-Tai AU - Huang RT LA - chi PT - English Abstract PT - Journal Article PT - Randomized Controlled Trial PL - China TA - Zhongguo Zhen Jiu JT - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JID - 8600658 RN - 0 (Inflammation Mediators) RN - 0 (Interleukin-2) RN - 0 (Tumor Necrosis Factor-alpha) RN - 130068-27-8 (Interleukin-10) SB - IM MH - *Acupuncture Analgesia MH - Adult MH - *Anesthesia, General MH - Cardiac Surgical Procedures MH - Female MH - Heart Diseases/blood/*immunology/*surgery MH - Humans MH - Inflammation Mediators/*blood MH - Interleukin-10/blood MH - Interleukin-2/blood MH - Male MH - Middle Aged MH - Perioperative Care MH - Tumor Necrosis Factor-alpha/blood MH - Young Adult EDAT- 2010/09/25 06:00 MHDA- 2010/10/13 06:00 CRDT- 2010/09/25 06:00 PHST- 2010/09/25 06:00 [entrez] PHST- 2010/09/25 06:00 [pubmed] PHST- 2010/10/13 06:00 [medline] PST - ppublish SO - Zhongguo Zhen Jiu. 2010 Jul;30(7):585-8.