PMID- 20863527
OWN - NLM
STAT- MEDLINE
DCOM- 20101116
LR  - 20221207
IS  - 1095-8673 (Electronic)
IS  - 0022-4804 (Linking)
VI  - 164
IP  - 1
DP  - 2010 Nov
TI  - Effects of subtotal gastrectomy and Roux-en-Y gastrojejunostomy on the clinical 
      outcome of type 2 diabetes mellitus.
PG  - e67-71
LID - 10.1016/j.jss.2010.07.004 [doi]
AB  - BACKGROUND: To investigate the effects of subtotal gastrectomy and Roux-en-Y 
      gastrojejunostomy on the clinical outcome of patients with type 2 diabetes 
      mellitus (T2DM). METHODS: We performed retrospective analysis of 21 patients with 
      T2DM operated due to stomach cancer and upper gastrointestinal tract ulcer 
      between January 2001 and June 2008. RESULTS: The body mass index (BMl) of all 
      patients was <30 kg/m(2). The mean postoperative follow-up period was 26.6 mo 
      (range, 6 mo-5 y). Subtotal gastrectomy and Roux-en-Y gastrojejunostomy 
      remarkably lowered the levels of fasting plasma glucose (FPG), 2 h postprandial 
      plasma glucose (2hPG), and glycated hemoglobin (HbA1c). Overall, 12 patients 
      (57.1%) achieved adequate glycemic control (HbA1c < 7%) without antidiabetic 
      medication and five patients (23.8%) showed good improvement. The total 
      effectiveness rate of the surgery in T2DM patients was 81.0%. CONCLUSION: 
      Subtotal gastrectomy and Roux-en-Y gastrojejunostomy appear to be effective 
      treatment modalities for controlling T2DM in patients with BMl <30 kg/m(2). 
      However, more studies with long follow-up period and large number of patients are 
      necessary to clarify the benefits of this procedure.
CI  - Copyright (c) 2010 Elsevier Inc. All rights reserved.
FAU - Yang, Juntao
AU  - Yang J
AD  - Department of Hepatobiliary Surgery, Institute of Surgery Research, Daping 
      Hospital, Third Military Medical University, Chongqing, China.
FAU - Li, Chunxue
AU  - Li C
FAU - Liu, Hongming
AU  - Liu H
FAU - Gu, Hongguang
AU  - Gu H
FAU - Chen, Ping
AU  - Chen P
FAU - Liu, Baohua
AU  - Liu B
LA  - eng
PT  - Journal Article
DEP - 20100730
PL  - United States
TA  - J Surg Res
JT  - The Journal of surgical research
JID - 0376340
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (hemoglobin A1c protein, human)
SB  - IM
MH  - Aged
MH  - Blood Glucose/metabolism
MH  - Body Mass Index
MH  - Body Weight
MH  - Diabetes Mellitus, Type 2/*complications/drug therapy/*surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Gastrectomy/*methods
MH  - *Gastric Bypass
MH  - Glycated Hemoglobin/metabolism
MH  - Humans
MH  - Hypoglycemic Agents/therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Stomach Neoplasms/complications/surgery
MH  - Stomach Ulcer/complications/*surgery
MH  - Treatment Outcome
EDAT- 2010/09/25 06:00
MHDA- 2010/11/17 06:00
CRDT- 2010/09/25 06:00
PHST- 2010/01/11 00:00 [received]
PHST- 2010/06/01 00:00 [revised]
PHST- 2010/07/02 00:00 [accepted]
PHST- 2010/09/25 06:00 [entrez]
PHST- 2010/09/25 06:00 [pubmed]
PHST- 2010/11/17 06:00 [medline]
AID - S0022-4804(10)00616-5 [pii]
AID - 10.1016/j.jss.2010.07.004 [doi]
PST - ppublish
SO  - J Surg Res. 2010 Nov;164(1):e67-71. doi: 10.1016/j.jss.2010.07.004. Epub 2010 Jul 
      30.