PMID- 20875239
OWN - NLM
STAT- MEDLINE
DCOM- 20110111
LR  - 20190513
IS  - 1945-239X (Electronic)
IS  - 0021-9665 (Linking)
VI  - 48
IP  - 9
DP  - 2010 Oct
TI  - Determination of six phthalic acid esters in orange juice packaged by PVC bottle 
      using SPE and HPLC-UV: application to the migration study.
PG  - 760-5
AB  - A high-performance liquid chromatographic assay is described for the 
      determination of six phthalic acid esters (PAEs) in orange juice packaged in 
      polyvinyl chloride (PVC) bottle. Samples were extracted by solid-phase extraction 
      (SPE) cartridges and separated by a C(1)(8) column. The calibration curves were all 
      linear with a correlation coefficient r > 0.9900. The limits of detection for the 
      assay ranged from 2.6 to 13.8 ng/mL. Expressed as the within- and between-day 
      coefficient of variation (CV), precision was 1.4-13.4% and 1.9-13.3%, 
      respectively, and relative errors were 7.6-12.8% and -9.0-14.2%, respectively. 
      The recovery ranged from 76.8 to 112.3% with the CV from 0.3 to 11.3%. The 
      proposed methodology was applied for studing the migration of the selected PAEs 
      into orange juice packaged in PVC bottle. Di-ethyl phthalate (DEP) and 
      di-(2-ethylhexyl) phthalate (DEHP) were detected in the orange juice without the 
      other four PAEs. Concentrations would increase with the storage time and reach up 
      to 0.385 mug/mL and 0.662 mug/mL, respectively, when the expiration date arrived. 
      The level of DEHP was about 110 times higher than the limiting one in drink water 
      (6 ppb) regulated by U.S. EPA. Results suggest that PVC plasticized by DEHP 
      should not be used as the packaging material for orange juice.
FAU - Guo, Zhiyong
AU  - Guo Z
AD  - Faculty of Materials Science and Chemical Engineering, The State Key Laboratory 
      Base of Novel Functional Materials and Preparation Science, Ningbo University, 
      315211 Ningbo, China. guozhiyong@nbu.edu.cn
FAU - Wei, Danyi
AU  - Wei D
FAU - Wang, Meili
AU  - Wang M
FAU - Wang, Sui
AU  - Wang S
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Chromatogr Sci
JT  - Journal of chromatographic science
JID - 0173225
RN  - 0 (Phthalic Acids)
RN  - 9002-86-2 (Polyvinyl Chloride)
SB  - IM
MH  - Beverages/*analysis
MH  - Chromatography, High Pressure Liquid/*methods
MH  - *Citrus sinensis
MH  - *Food Packaging
MH  - Linear Models
MH  - Phthalic Acids/*analysis
MH  - Polyvinyl Chloride/*chemistry
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Solid Phase Extraction/*methods
MH  - Spectrophotometry, Ultraviolet
EDAT- 2010/09/30 06:00
MHDA- 2011/01/12 06:00
CRDT- 2010/09/30 06:00
PHST- 2010/09/30 06:00 [entrez]
PHST- 2010/09/30 06:00 [pubmed]
PHST- 2011/01/12 06:00 [medline]
AID - 10.1093/chromsci/48.9.760 [doi]
PST - ppublish
SO  - J Chromatogr Sci. 2010 Oct;48(9):760-5. doi: 10.1093/chromsci/48.9.760.