PMID- 20887994
OWN - NLM
STAT- MEDLINE
DCOM- 20110121
LR  - 20131121
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1217
IP  - 45
DP  - 2010 Nov 5
TI  - Molecular complex-based dispersive liquid-liquid microextraction: analysis of 
      polar compounds in aqueous solution.
PG  - 7010-6
LID - 10.1016/j.chroma.2010.09.013 [doi]
AB  - A novel molecular complex-based dispersive liquid-liquid microextraction (DLLME) 
      method was established via hydrogen bond interaction between the extractant and 
      the analytes. In this approach, tri-n-butylphosphate (TBP), a Lewis base, was 
      directly used, instead of the traditional water-immiscible organic solvents, as 
      the extractant for DLLME. The phenols (p-benzenediol, m-benzenediol, 
      o-benzenediol and phenol), which are typical Lewis acids, were successfully 
      extracted from environmental aqueous samples. In addition, phase separation was 
      achieved in a disposable polyethylene pipet with the open and narrow tip upside, 
      for a collection of the above extractant layer, i.e. TBP. To achieve satisfactory 
      extraction performance, several extraction parameters, such as type of extractant 
      solvents, extractant volume, pH of sample solution, ionic strength of sample 
      solution and extraction time, were optimized. Additionally, the proposed method 
      was applied to environmental water samples. Under the optimized conditions, the 
      limits of detection and limits of quantification for the phenols were 7-29 and 
      25-98 mug/L, respectively. The calibration curves showed good linearity 
      (r(2)>/=0.9961) over the investigated concentration range. The repeatability of the 
      method was investigated by evaluating the intra- and inter-day precisions. The 
      relative standard deviations (RSDs) obtained were lower than 11.2% and 13.9% at 
      different concentration levels. The recoveries ranged from 83.2% to 117.8%, with 
      RSDs less than 13.1%. The developed approach provides a new way to facilitate 
      DLLME of organic polar compounds from aqueous solutions. Moreover, it enables a 
      convenient collection of solvent less dense making use of a cheap and disposable 
      polyethylene pipet.
CI  - Copyright (c) 2010 Elsevier B.V. All rights reserved.
FAU - Hu, Xi-Zhou
AU  - Hu XZ
AD  - Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of 
      Education), Department of Chemistry, Wuhan University, Wuhan 430072, China.
FAU - Wu, Jian-Hong
AU  - Wu JH
FAU - Feng, Yu-Qi
AU  - Feng YQ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100921
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Organophosphates)
RN  - 0 (Phenols)
RN  - 0 (Sewage)
RN  - 059QF0KO0R (Water)
RN  - 95UAS8YAF5 (tributyl phosphate)
SB  - IM
MH  - Chemical Fractionation/*methods
MH  - Hydrogen-Ion Concentration
MH  - Hydrophobic and Hydrophilic Interactions
MH  - Linear Models
MH  - Organophosphates/chemistry
MH  - Phenols/analysis/*isolation & purification
MH  - Reproducibility of Results
MH  - Rivers/chemistry
MH  - Sensitivity and Specificity
MH  - Sewage/chemistry
MH  - Water/*chemistry
EDAT- 2010/10/05 06:00
MHDA- 2011/01/22 06:00
CRDT- 2010/10/05 06:00
PHST- 2010/07/18 00:00 [received]
PHST- 2010/09/04 00:00 [revised]
PHST- 2010/09/07 00:00 [accepted]
PHST- 2010/10/05 06:00 [entrez]
PHST- 2010/10/05 06:00 [pubmed]
PHST- 2011/01/22 06:00 [medline]
AID - S0021-9673(10)01217-3 [pii]
AID - 10.1016/j.chroma.2010.09.013 [doi]
PST - ppublish
SO  - J Chromatogr A. 2010 Nov 5;1217(45):7010-6. doi: 10.1016/j.chroma.2010.09.013. 
      Epub 2010 Sep 21.