PMID- 20923489
OWN - NLM
STAT- MEDLINE
DCOM- 20110202
LR  - 20221207
IS  - 1753-0407 (Electronic)
IS  - 1753-0407 (Linking)
VI  - 2
IP  - 2
DP  - 2010 Jun
TI  - Epidemiology of Type 2 diabetes mellitus in Aleppo, Syria.
PG  - 85-91
LID - 10.1111/j.1753-0407.2009.00063.x [doi]
AB  - BACKGROUND: Type 2 diabetes mellitus (T2DM) is considerable public health 
      problem, but data on the prevalence and correlates of T2DM in Syria are scarce. 
      The aim of the present study was to establish reliable estimates of the 
      prevalence of T2DM in Syria. METHODS: A cross-sectional, population-based survey 
      was conducted in Aleppo, Syria (population 2.5 million), in 2006. The study was 
      conducted on a random sample of 1168 subjects >/=25 years of age (47.7% men; mean 
      age 44.7 +/- 12.7 years). Information regarding a personal history of diabetes and 
      other risk factors was collected, followed by measurement of weight, height, and 
      the waist:hip ratio (WHR). Of the 1168 participants, 806 provided fasting blood 
      samples that were analyzed for fasting plasma glucose (FPG) and HbA1c. RESULTS: 
      The prevalence of T2DM based on FPG >/=126 mg/dL and HbA1c >/=6.5% was 15.6% (11.2% 
      self-reported; 5.0% diagnosed) and 14.8%, respectively. The prevalence of 
      impaired fasting glucose (FPG >/=110 and <126 mg/dL) was 8.6%. There was a 
      significant positive association between T2DM and age, WHR, a family history of 
      T2DM, and body mass index (BMI) and an inverse association between T2DM and 
      physical activity (P < 0.01 for all). Multivariate analysis showed that age, BMI, 
      WHR, and a family history of T2DM were the most important factors associated with 
      T2DM. Only 16.7% of treated cases of T2DM were under control (i.e. HbA1c <7%). 
      CONCLUSIONS: Based on the results obtained in our sample, T2DM is widespread in 
      Syria. Many of those with T2DM are unaware of their disease and most have 
      unsatisfactory control of their disease.
CI  - (c) 2009 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and 
      Blackwell Publishing Asia Pty Ltd.
FAU - Albache, Nizar
AU  - Albache N
AD  - Syrian Center for Tobacco Studies, Faculty of Medicine, University of Aleppo, 
      Aleppo, Syria.
FAU - Al Ali, Radwan
AU  - Al Ali R
FAU - Rastam, Samer
AU  - Rastam S
FAU - Fouad, Fouad M
AU  - Fouad FM
FAU - Mzayek, Fawaz
AU  - Mzayek F
FAU - Maziak, Wasim
AU  - Maziak W
LA  - eng
GR  - R01DA024876-01/DA/NIDA NIH HHS/United States
GR  - TW05962/TW/FIC NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20091102
PL  - Australia
TA  - J Diabetes
JT  - Journal of diabetes
JID - 101504326
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Glucose/analysis
MH  - Body Mass Index
MH  - Developing Countries/statistics & numerical data
MH  - Diabetes Mellitus, Type 2/blood/*epidemiology
MH  - Ethnicity
MH  - Female
MH  - Global Health
MH  - Glycated Hemoglobin/metabolism
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Religion
MH  - Surveys and Questionnaires
MH  - Syria/epidemiology
EDAT- 2010/10/07 06:00
MHDA- 2011/02/03 06:00
CRDT- 2010/10/07 06:00
PHST- 2010/10/07 06:00 [entrez]
PHST- 2010/10/07 06:00 [pubmed]
PHST- 2011/02/03 06:00 [medline]
AID - 10.1111/j.1753-0407.2009.00063.x [doi]
PST - ppublish
SO  - J Diabetes. 2010 Jun;2(2):85-91. doi: 10.1111/j.1753-0407.2009.00063.x. Epub 2009 
      Nov 2.