PMID- 20923535
OWN - NLM
STAT- MEDLINE
DCOM- 20110121
LR  - 20101006
IS  - 1753-0407 (Electronic)
IS  - 1753-0407 (Linking)
VI  - 1
IP  - 3
DP  - 2009 Sep
TI  - Progress in diabetes research in China.
PG  - 163-72
LID - 10.1111/j.1753-0407.2009.00037.x [doi]
AB  - The prevalence of diabetes, especially Type 2 diabetes mellitus (T2DM), is 
      increasing markedly throughout the world, including in China. Because T2DM and 
      its complications are associated with considerable socioeconomic burden and 
      mortality, there is increasing interest in developing strategies to prevent or 
      delay progression of the disease. In recent decades, many researchers have 
      focused on the mechanism of onset of diabetes, as well as examining the benefits 
      of various interventions in subjects with different glucose tolerance status to 
      prevent or delay development of the disease. In the present article, we focus on 
      five areas (epidemiology, early intervention, insulin sensitivity and beta-cell 
      function, adipocytokines, and traditional Chinese medicine) to review the 
      progress of research into diabetes in China today. The prevalence of diabetes in 
      China is one of the highest in the world. However, with lifestyle interventions 
      and appropriate pharmacological therapies (including traditional Chinese 
      medicine), T2DM may be prevented, well controlled, or even put into remission. 
      Accurate estimation of insulin secretion and insulin sensitivity, as well as 
      better characterization of the physiological function of adipocytokines, could 
      give us a better understanding of the basic mechanisms underlying the onset of 
      diabetes and could lead to better interventions in people with impaired glucose 
      tolerance and T2DM.
CI  - (c) 2009 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and 
      Blackwell Publishing Asia Pty Ltd.
FAU - Ning, Guang
AU  - Ning G
AD  - Shanghai Clinical Center for Endocrine and Metabolic Diseases, Rui-Jin Hospital, 
      Shanghai Jiao Tong University School of Medicine, China. guangning@medmail.com.cn
FAU - Hong, Jie
AU  - Hong J
FAU - Bi, Yufang
AU  - Bi Y
FAU - Gu, Weiqiong
AU  - Gu W
FAU - Zhang, Yifei
AU  - Zhang Y
FAU - Zhang, Zhiguo
AU  - Zhang Z
FAU - Huang, Yun
AU  - Huang Y
FAU - Wang, Weiqing
AU  - Wang W
FAU - Li, Xiaoying
AU  - Li X
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20090630
PL  - Australia
TA  - J Diabetes
JT  - Journal of diabetes
JID - 101504326
RN  - 0 (Hypoglycemic Agents)
SB  - IM
MH  - China/epidemiology
MH  - Diabetes Mellitus/epidemiology/*therapy
MH  - Diabetes Mellitus, Type 2/epidemiology/prevention & control
MH  - Humans
MH  - Hypoglycemic Agents/therapeutic use
MH  - Medicine, Chinese Traditional
MH  - Research
EDAT- 2010/10/07 06:00
MHDA- 2011/01/22 06:00
CRDT- 2010/10/07 06:00
PHST- 2010/10/07 06:00 [entrez]
PHST- 2010/10/07 06:00 [pubmed]
PHST- 2011/01/22 06:00 [medline]
AID - 10.1111/j.1753-0407.2009.00037.x [doi]
PST - ppublish
SO  - J Diabetes. 2009 Sep;1(3):163-72. doi: 10.1111/j.1753-0407.2009.00037.x. Epub 
      2009 Jun 30.