PMID- 20936560
OWN - NLM
STAT- MEDLINE
DCOM- 20110202
LR  - 20160526
IS  - 1532-4117 (Electronic)
IS  - 1093-4529 (Linking)
VI  - 45
IP  - 14
DP  - 2010 Dec
TI  - Deriving the aquatic predicted no-effect concentrations (PNECs) of three 
      chlorophenols for the Taihu Lake, China.
PG  - 1823-31
LID - 10.1080/10934529.2010.520495 [doi]
AB  - The Predicted No-Effect Concentration (PNEC) is a key for ecological risk 
      assessment. In this paper, the aquatic species existing widely in the Taihu Lake 
      were selected, and their toxicity data to 2,4-dichlorophenol (2,4-DCP), 
      2,4,6-trichlorophenol (2,4,6-TCP) and pentachlorophenol (PCP) were collected. The 
      PNECs of 2,4-DCP; 2,4,6-TCP; and PCP were derived using three different 
      approaches, i.e., the assessment factor (AF), species sensitivity distribution 
      (SSD) as well as an eco-toxicological model (AQUATOX). As the results, PNEC(AF)s 
      were 2.18 mug L(-1), 2.53 mug L(-1) and 0.26 mug L(-1), and PNEC(SSD)s were 77 mug 
      L(-1), 197 mug L(-1) and 10 mug L(-1), respectively for 2,4-DCP; 2,4,6-TCP; and PCP 
      respectively. Based on the aquatic conditions of the Taihu Lake, the derived 
      site-specific PNEC(AQUATOX)s were 15 mug L(-1), 67 mug L(-1) and 4 mug L(-1), 
      respectively. In general, the PNECs for three chlorophenols derived from 
      different approaches followed the declined order of PNEC(SSD) > PNEC(AQUATOX) > 
      PNEC(AF). The ratios of PNEC(AF) to PNEC(SSD) and PNEC(AQUATOX) to PNEC(SSD) for 
      three chlorophenols were 0.013-0.028 and 0.19-0.4, respectively. It indicated 
      that PNECs obtained using different approaches may vary and the one based on the 
      AF was the lowest. Therefore, PNEC(AF) can be seen as overprotective. The 
      PNEC(AQUATOX) values for three chlorophenols were less than the corresponding 
      PNEC(SSD) values, mostly because the indirect effects were considered in the 
      ecological model.
FAU - Lei, Bing L
AU  - Lei BL
AD  - State Key Laboratory of Environmental Aquatic Chemistry, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.
FAU - Huang, Sheng B
AU  - Huang SB
FAU - Jin, Xiao W
AU  - Jin XW
FAU - Wang, Zijian
AU  - Wang Z
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Environ Sci Health A Tox Hazard Subst Environ Eng
JT  - Journal of environmental science and health. Part A, Toxic/hazardous substances & 
      environmental engineering
JID - 9812551
RN  - 0 (Chlorophenols)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Animals
MH  - Aquatic Organisms/*drug effects/growth & development
MH  - China
MH  - Chlorophenols/*analysis/chemistry/toxicity
MH  - Ecotoxicology
MH  - Environmental Monitoring/*methods/statistics & numerical data
MH  - Fresh Water/*analysis
MH  - Models, Biological
MH  - Monte Carlo Method
MH  - No-Observed-Adverse-Effect Level
MH  - Predictive Value of Tests
MH  - Risk Assessment
MH  - Species Specificity
MH  - Water Pollutants, Chemical/*analysis/chemistry/toxicity
EDAT- 2010/10/12 06:00
MHDA- 2011/02/03 06:00
CRDT- 2010/10/12 06:00
PHST- 2010/10/12 06:00 [entrez]
PHST- 2010/10/12 06:00 [pubmed]
PHST- 2011/02/03 06:00 [medline]
AID - 927853822 [pii]
AID - 10.1080/10934529.2010.520495 [doi]
PST - ppublish
SO  - J Environ Sci Health A Tox Hazard Subst Environ Eng. 2010 Dec;45(14):1823-31. 
      doi: 10.1080/10934529.2010.520495.