PMID- 2094629 OWN - NLM STAT- MEDLINE DCOM- 19910628 LR - 20161020 IS - 0257-7712 (Print) IS - 0257-7712 (Linking) VI - 21 IP - 4 DP - 1990 Sep TI - [Effects of high carbohydrate and high fat diet on plasma apolipoproteins AI, AII, B100, CI, CII, CIII and E in normal and hypertriglyceridemic humans]. PG - 349-53 AB - Effects of high carbohydrate (CHO) and high fat diet on plasma apolipoproteins (apo) AI, AII, B100, CI, CII, CIII and E were assessed in 10 healthy subjects and 10 patients with endogenous hypertriglyceridemia. High CHO diet consisted of 80% CHO, 5% fat and 15% protein of total calories, and high fat diet consisted of 40% CHO, 45% fat and 15% protein. After 5 days normal diet (60% of total calories from CHO, 25% from from fat and 15% from protein), the subjects studied received sequentially high CHO diet and normal diet for 5 days and high fat diet and normal diet for 5 days. Fasting blood samples were drawn on days 1, 3, and 5 of high CHO and high fat diet period, and 5 days after taking normal diet. Results showed that fasting plasma apo AI slightly decreased (P less than 0.01) on day 3 of the high CHO diet period and slightly increased (P less than 0.01) on day 3 of the high fat diet period, plasma apo AII increased after intake of high CHO diet, but no changes were observed after the subjects were placed on high fat diet. Fasting plasma apo B100 decreased (P less than 0.001) in hypertriglyceridemics on the 3rd day of the high CHO diet, but no differences were noted in normal subjects on the same diet. On the 3rd day of the high fat diet period, apo B100 increased (P less than 0.01) in normal subjects, but no changes were found in hypertriglyceridemics. Apo CII and CIII levels declined during the high CHO diet period but increased in normal subjects after intake of high fat died.(ABSTRACT TRUNCATED AT 250 WORDS) FAU - Liu, B AU - Liu B FAU - Wu, Z AU - Wu Z FAU - Zhang, Z AU - Zhang Z FAU - Fan, P AU - Fan P FAU - Liu, M AU - Liu M FAU - Fu, M AU - Fu M FAU - Luo, J AU - Luo J LA - chi PT - English Abstract PT - Journal Article PL - China TA - Hua Xi Yi Ke Da Xue Xue Bao JT - Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao JID - 8609552 RN - 0 (Apolipoprotein B-100) RN - 0 (Apolipoproteins) RN - 0 (Apolipoproteins A) RN - 0 (Apolipoproteins B) RN - 0 (Apolipoproteins C) RN - 0 (Apolipoproteins E) RN - 0 (Dietary Carbohydrates) RN - 0 (Dietary Fats) SB - IM MH - Adult MH - Apolipoprotein B-100 MH - Apolipoproteins/*blood MH - Apolipoproteins A/blood MH - Apolipoproteins B/blood MH - Apolipoproteins C/blood MH - Apolipoproteins E/blood MH - Dietary Carbohydrates/*administration & dosage MH - Dietary Fats/*administration & dosage MH - Female MH - Humans MH - Hypertriglyceridemia/*blood MH - Male MH - Middle Aged EDAT- 1990/09/01 00:00 MHDA- 1990/09/01 00:01 CRDT- 1990/09/01 00:00 PHST- 1990/09/01 00:00 [pubmed] PHST- 1990/09/01 00:01 [medline] PHST- 1990/09/01 00:00 [entrez] PST - ppublish SO - Hua Xi Yi Ke Da Xue Xue Bao. 1990 Sep;21(4):349-53.