PMID- 20947193
OWN - NLM
STAT- MEDLINE
DCOM- 20130129
LR  - 20120120
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 154
IP  - 3
DP  - 2012 Feb 9
TI  - Clinical impact of screening for sleep related breathing disorders in atrial 
      fibrillation.
PG  - 256-8
LID - 10.1016/j.ijcard.2010.09.034 [doi]
AB  - OBJECTIVE: The aim of this study was to quantify daytime symptoms in atrial 
      fibrillation (AF) patients with and without sleep related breathing disorders 
      (SRBD). BACKGROUND: SRBD are common in patients with AF but little is known about 
      daytime symptoms among those with SRBD. METHODS: Patients with AF admitted to 
      clinics of two tertiary referral hospitals for a variety of different 
      cardiovascular diseases were screened with a trans-nasal airflow measurement 
      device allowing measurement of the apnea-hypopnea-index. Data on cardiac risk 
      factors, left ventricular ejection fraction (LVEF) and cardiac medication were 
      collected. Presence of SRBD was defined as an AHI >/= 15/h. The Epworth sleepiness 
      scale (ESS) was used to quantify daytime symptoms. RESULTS: Of 102 screened 
      patients 8 were excluded due to device malfunction (n=1), dislocation of nasal 
      cannula (n=6), or hyperthyroidism (n=1). Among the remaining 94 patients, 40 
      (43%) were diagnosed with SRBD. Patients with and without SRBD had similar age, 
      body mass index, LVEF and cardiac medication. The prevalence of coronary artery 
      disease was higher in patients with SRBD than in those without (50 vs. 17%; 
      p=0.0007). ESS score was low and similar in both groups (no SRBD: median 4, 
      interquartile range (IQR) 2-4 vs. SRBD: 5, IQR 3-8; p=0.14). Only 6/40 (5%) of 
      the patients underwent overnight polysomnography and 2 (5%) started CPAP 
      ventilation during follow-up. CONCLUSIONS: Even though SRBD are common in 
      patients with AF, the prevalence of daytime symptoms is rare. Consequently, most 
      patients will not initiate CPAP ventilation after positive SRBD screening.
CI  - Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.
FAU - Altmann, David R
AU  - Altmann DR
AD  - Division of Cardiology, Kantonsspital St. Gallen, Switzerland.
FAU - Ullmer, Elke
AU  - Ullmer E
FAU - Rickli, Hans
AU  - Rickli H
FAU - Maeder, Micha T
AU  - Maeder MT
FAU - Sticherling, Christian
AU  - Sticherling C
FAU - Schaer, Beat A
AU  - Schaer BA
FAU - Osswald, Stefan
AU  - Osswald S
FAU - Ammann, Peter
AU  - Ammann P
LA  - eng
PT  - Journal Article
DEP - 20101013
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
MH  - Aged
MH  - Atrial Fibrillation/*complications
MH  - Female
MH  - Humans
MH  - Male
MH  - Prevalence
MH  - Sleep Apnea Syndromes/diagnosis/*epidemiology/*etiology
EDAT- 2010/10/16 06:00
MHDA- 2013/01/30 06:00
CRDT- 2010/10/16 06:00
PHST- 2010/06/08 00:00 [received]
PHST- 2010/09/10 00:00 [accepted]
PHST- 2010/10/16 06:00 [entrez]
PHST- 2010/10/16 06:00 [pubmed]
PHST- 2013/01/30 06:00 [medline]
AID - S0167-5273(10)00729-1 [pii]
AID - 10.1016/j.ijcard.2010.09.034 [doi]
PST - ppublish
SO  - Int J Cardiol. 2012 Feb 9;154(3):256-8. doi: 10.1016/j.ijcard.2010.09.034. Epub 
      2010 Oct 13.