PMID- 20948872 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20110714 LR - 20211020 IS - 1757-5931 (Electronic) IS - 1757-5931 (Linking) VI - 2 DP - 2010 Feb 24 TI - Genetic screening for multiple endocrine neoplasia syndrome type 1 (MEN-1): when and how. LID - 14 [pii] LID - 10.3410/M2-14 [doi] AB - Multiple endocrine neoplasia syndrome type 1 (MEN1) syndrome has benefited from the identification of the gene whose mutations account for the genetic susceptibility to develop endocrine tumors. Asymptomatic MEN1 mutant carriers need to be clearly recognized because the gene-related mutations confer a high risk of multiple primary cancers, occur at younger ages, and affect multiple family members who inherit the cancer-predisposing genetic mutation. FAU - Falchetti, Alberto AU - Falchetti A AD - Department of Internal Medicine, University of Florence and Regional Centre for Hereditary Endocrine Tumors, Unit of Metabolic Bone Diseases, University Hospital of Careggi Viale G Pieraccini 6, 50139 Florence Italy. LA - eng PT - Journal Article DEP - 20100224 PL - England TA - F1000 Med Rep JT - F1000 medicine reports JID - 101506841 PMC - PMC2948394 EDAT- 2010/10/16 06:00 MHDA- 2010/10/16 06:01 PMCR- 2010/02/24 CRDT- 2010/10/16 06:00 PHST- 2010/10/16 06:00 [entrez] PHST- 2010/10/16 06:00 [pubmed] PHST- 2010/10/16 06:01 [medline] PHST- 2010/02/24 00:00 [pmc-release] AID - 14 [pii] AID - 10.3410/M2-14 [doi] PST - epublish SO - F1000 Med Rep. 2010 Feb 24;2:14. doi: 10.3410/M2-14.