PMID- 20951972
OWN - NLM
STAT- MEDLINE
DCOM- 20101217
LR  - 20220408
IS  - 1879-1891 (Electronic)
IS  - 0002-9394 (Linking)
VI  - 150
IP  - 6
DP  - 2010 Dec
TI  - Features associated with foveal retinal detachment in myopic macular 
      retinoschisis.
PG  - 863-70
LID - 10.1016/j.ajo.2010.06.023 [doi]
AB  - PURPOSE: To determine the retinal features seen on enhanced spectral-domain 
      optical coherence tomography (SD-OCT) associated with foveal retinal detachment 
      in eyes with myopic macular retinoschisis. DESIGN: Retrospective case series. 
      METHODS: We reviewed fundus photographs and conventional and enhanced SD-OCT 
      images of 21 eyes of 19 patients with myopic macular retinoschisis. Features seen 
      on enhanced SD-OCT images were identified and compared between eyes with and 
      without foveal detachment. RESULTS: On enhanced SD-OCT images, the retinoschisis 
      in the outer retina was accompanied by splitting in the inner plexiform layer 
      (IPL) in 11 eyes (50.0%) and a detachment of the inner limiting membrane (ILM) in 
      11 eyes (50.0%) in the superior and/or inferior peripheral macula; 9 eyes (42.9%) 
      had both features. Multiple columnar structures were seen throughout the outer 
      retinoschisis in 20 of 21 eyes (95.2%), and in ILM detachment/IPL retinoschisis 
      in all eyes. Thirteen eyes had or progressed to a foveal detachment; an ILM 
      detachment developed in 10 eyes (76.9%) with a foveal detachment and in 1 eye 
      (12.5%) without a foveal detachment (P = .008). IPL retinoschisis was detected in 
      8 eyes (61.5%) with a foveal detachment and 3 eyes (37.5%) without a foveal 
      detachment, but this difference was not significant. CONCLUSIONS: An ILM 
      detachment in the superior and/or inferior peripheral macula was associated with 
      a foveal retinal detachment in highly myopic eyes with macular retinoschisis. 
      This feature may indicate strong tractional forces on the ILM that are 
      transmitted to the outer retina through the dense columnar structures, resulting 
      in a foveal retinal detachment.
CI  - Copyright (c) 2010 Elsevier Inc. All rights reserved.
FAU - Fujimoto, Masahiro
AU  - Fujimoto M
AD  - Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School 
      of Medicine, Kyoto, Japan.
FAU - Hangai, Masanori
AU  - Hangai M
FAU - Suda, Kenji
AU  - Suda K
FAU - Yoshimura, Nagahisa
AU  - Yoshimura N
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20101016
PL  - United States
TA  - Am J Ophthalmol
JT  - American journal of ophthalmology
JID - 0370500
SB  - IM
MH  - Adult
MH  - Aged
MH  - Basement Membrane/pathology
MH  - Disease Progression
MH  - Female
MH  - Fovea Centralis/*pathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myopia/complications/*diagnosis
MH  - Retinal Detachment/*diagnosis/etiology
MH  - Retinoschisis/*diagnosis/etiology
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Tomography, Optical Coherence
MH  - Visual Acuity
EDAT- 2010/10/19 06:00
MHDA- 2010/12/18 06:00
CRDT- 2010/10/19 06:00
PHST- 2010/03/06 00:00 [received]
PHST- 2010/06/15 00:00 [revised]
PHST- 2010/06/15 00:00 [accepted]
PHST- 2010/10/19 06:00 [entrez]
PHST- 2010/10/19 06:00 [pubmed]
PHST- 2010/12/18 06:00 [medline]
AID - S0002-9394(10)00449-6 [pii]
AID - 10.1016/j.ajo.2010.06.023 [doi]
PST - ppublish
SO  - Am J Ophthalmol. 2010 Dec;150(6):863-70. doi: 10.1016/j.ajo.2010.06.023. Epub 
      2010 Oct 16.