PMID- 20954642
OWN - NLM
STAT- MEDLINE
DCOM- 20110331
LR  - 20110630
IS  - 1938-2375 (Electronic)
IS  - 1542-8877 (Linking)
VI  - 41
IP  - 6
DP  - 2010 Nov-Dec
TI  - Optical coherence tomography/scanning laser ophthalmoscopy imaging of optic nerve 
      head drusen.
PG  - 614-21
LID - 10.3928/15428877-20100929-07 [doi]
AB  - BACKGROUND AND OBJECTIVE: To evaluate optical coherence tomography/scanning laser 
      ophthalmoscopy (OCT/SLO) imaging for optic nerve head drusen (ONHD). PATIENTS AND 
      METHODS: Nine consecutive eyes with ONHD were imaged. Each underwent visual field 
      testing, 20-MHz B-scan ultrasonography, photography, and OCT/SLO imaging of the 
      nerve head. Similar evaluation was performed on 12 matched, disease-free control 
      eyes for comparison. RESULTS: OCT/SLO imaging of ONHD demonstrated lucencies 
      (100%), variable amounts of displacement, and thickening of the overlying nerve 
      fiber layer, as well as disorganization of the adjacent retinal pigment 
      epithelium (44%). Optic nerve head topography was measured (using horizontal and 
      vertical electronic calipers). Mean disc diameter was 1.81 mm (range: 1.49 to 
      2.12 mm). All ONHD demonstrated anterior displacement of the base of the optic 
      nerve cup (shallowing) compared to controls. The cup base was a mean +0.32 mm 
      anterior to the retinal pigment epithelium for ONHD versus -0.23 mm for normal 
      controls. CONCLUSION: OCT/SLO revealed unique and clinically helpful views of 
      ONHD.
CI  - Copyright 2010, SLACK Incorporated.
FAU - Patel, Nandesh N
AU  - Patel NN
AD  - The New York Eye Cancer Center, New York, NY, USA.
FAU - Shulman, Julia P
AU  - Shulman JP
FAU - Chin, Kimberly J
AU  - Chin KJ
FAU - Finger, Paul T
AU  - Finger PT
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100929
PL  - United States
TA  - Ophthalmic Surg Lasers Imaging
JT  - Ophthalmic surgery, lasers & imaging : the official journal of the International 
      Society for Imaging in the Eye
JID - 101155780
SB  - IM
MH  - Adult
MH  - Aged
MH  - Female
MH  - Humans
MH  - Male
MH  - *Microscopy, Confocal
MH  - Middle Aged
MH  - Ophthalmoscopy/*methods
MH  - Optic Disk/*pathology
MH  - Optic Disk Drusen/*diagnosis
MH  - *Tomography, Optical Coherence
EDAT- 2010/10/20 06:00
MHDA- 2011/04/01 06:00
CRDT- 2010/10/20 06:00
PHST- 2009/11/05 00:00 [received]
PHST- 2010/07/28 00:00 [accepted]
PHST- 2010/10/20 06:00 [entrez]
PHST- 2010/10/20 06:00 [pubmed]
PHST- 2011/04/01 06:00 [medline]
AID - 10.3928/15428877-20100929-07 [doi]
PST - ppublish
SO  - Ophthalmic Surg Lasers Imaging. 2010 Nov-Dec;41(6):614-21. doi: 
      10.3928/15428877-20100929-07. Epub 2010 Sep 29.