PMID- 20956066 OWN - NLM STAT- MEDLINE DCOM- 20110511 LR - 20220316 IS - 1873-7897 (Electronic) IS - 0887-6185 (Print) IS - 0887-6185 (Linking) VI - 25 IP - 2 DP - 2011 Mar TI - Gender differences in PTSD symptoms: an exploration of peritraumatic mechanisms. PG - 209-16 LID - 10.1016/j.janxdis.2010.09.004 [doi] AB - Females are at higher risk than males for developing posttraumatic stress disorder symptoms (PTSS) following exposure to trauma, which may stem from gender differences in initial physiological and psychological responses to trauma. The present study aimed to examine a number of peri- and initial posttraumatic reactions to motor vehicle accidents (MVAs) to determine the extent to which they contributed to gender differences in PTSS. 356 adult MVA survivors (211 males and 145 females) reported on peritraumatic dissociation, perception of life threat and initial PTSS. In addition, heart rate and urinary cortisol levels were collected in-hospital. 6 weeks and 6 months later, PTSS were assessed via clinical interviews. Results suggested that initial PTSS and peritraumatic dissociation were marginally significant mediators at 6-week follow-up and significant mediators at 6-month follow-up, providing partial support for the hypothesis that initial responses to trauma may account for observed gender differences in PTSS development. CI - Copyright (c) 2010 Elsevier Ltd. All rights reserved. FAU - Irish, Leah A AU - Irish LA AD - Kent State University, Department of Psychology, Kent, OH, United States. FAU - Fischer, Beth AU - Fischer B FAU - Fallon, William AU - Fallon W FAU - Spoonster, Eileen AU - Spoonster E FAU - Sledjeski, Eve M AU - Sledjeski EM FAU - Delahanty, Douglas L AU - Delahanty DL LA - eng GR - R01 MH062042/MH/NIMH NIH HHS/United States GR - R01 MH062042-04/MH/NIMH NIH HHS/United States GR - R01 MH62042/MH/NIMH NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20100917 PL - Netherlands TA - J Anxiety Disord JT - Journal of anxiety disorders JID - 8710131 SB - IM MH - Accidents, Traffic/*psychology MH - Adolescent MH - Adult MH - Analysis of Variance MH - Female MH - Humans MH - Injury Severity Score MH - Life Change Events MH - Male MH - Psychiatric Status Rating Scales MH - Risk Factors MH - *Sex Characteristics MH - Stress Disorders, Post-Traumatic/*diagnosis/*psychology MH - Survivors/*psychology PMC - PMC3031659 MID - NIHMS247876 EDAT- 2010/10/20 06:00 MHDA- 2011/05/12 06:00 PMCR- 2012/03/01 CRDT- 2010/10/20 06:00 PHST- 2010/02/09 00:00 [received] PHST- 2010/08/14 00:00 [revised] PHST- 2010/09/09 00:00 [accepted] PHST- 2010/10/20 06:00 [entrez] PHST- 2010/10/20 06:00 [pubmed] PHST- 2011/05/12 06:00 [medline] PHST- 2012/03/01 00:00 [pmc-release] AID - S0887-6185(10)00186-6 [pii] AID - 10.1016/j.janxdis.2010.09.004 [doi] PST - ppublish SO - J Anxiety Disord. 2011 Mar;25(2):209-16. doi: 10.1016/j.janxdis.2010.09.004. Epub 2010 Sep 17.