PMID- 20965490
OWN - NLM
STAT- MEDLINE
DCOM- 20110314
LR  - 20220409
IS  - 1097-6868 (Electronic)
IS  - 0002-9378 (Linking)
VI  - 204
IP  - 2
DP  - 2011 Feb
TI  - Adverse events in pregnant women following administration of trivalent 
      inactivated influenza vaccine and live attenuated influenza vaccine in the 
      Vaccine Adverse Event Reporting System, 1990-2009.
PG  - 146.e1-7
LID - 10.1016/j.ajog.2010.08.050 [doi]
AB  - OBJECTIVE: The objective of the study was to characterize reports to the Vaccine 
      Adverse Event Reporting System (VAERS) in pregnant women who received seasonal 
      influenza vaccines to assess for potential vaccine safety concerns. STUDY DESIGN: 
      We searched VAERS for reports of adverse events (AEs) in pregnant women who 
      received trivalent inactivated influenza vaccine (TIV) from July 1, 1990 through 
      June 30, 2009, or live attenuated influenza vaccine (LAIV) from July 1, 2003, 
      through June 30, 2009. RESULTS: A total of 148 reports after TIV and 27 reports 
      after LAIV were identified. Twenty TIV (13.5%) and 1 LAIV (4%) reports were 
      classified as serious. No specific AEs were reported in 30 TIV (20.3%) and 16 
      LAIV (59%) reports. The most common pregnancy-specific AE was spontaneous 
      abortion: 17 after TIV (11.5%) and 3 after LAIV (11%). The reporting rate of 
      spontaneous abortion was 1.9 per million pregnant women vaccinated. CONCLUSION: 
      No unusual patterns of pregnancy complications or fetal outcomes were observed in 
      the VAERS reports of pregnant women after the administration of TIV or LAIV.
CI  - Published by Mosby, Inc.
FAU - Moro, Pedro L
AU  - Moro PL
AD  - Immunization Safety Office, Division of Healthcare Quality Promotion/National 
      Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control 
      and Prevention, Atlanta, GA, USA.
FAU - Broder, Karen
AU  - Broder K
FAU - Zheteyeva, Yenlik
AU  - Zheteyeva Y
FAU - Walton, Kimp
AU  - Walton K
FAU - Rohan, Patricia
AU  - Rohan P
FAU - Sutherland, Andrea
AU  - Sutherland A
FAU - Guh, Alice
AU  - Guh A
FAU - Haber, Penina
AU  - Haber P
FAU - Destefano, Frank
AU  - Destefano F
FAU - Vellozzi, Claudia
AU  - Vellozzi C
LA  - eng
PT  - Journal Article
DEP - 20101020
PL  - United States
TA  - Am J Obstet Gynecol
JT  - American journal of obstetrics and gynecology
JID - 0370476
RN  - 0 (Influenza Vaccines)
RN  - 0 (Vaccines, Attenuated)
SB  - IM
MH  - Adverse Drug Reaction Reporting Systems/*statistics & numerical data
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Influenza Vaccines/administration & dosage/*adverse effects
MH  - Influenza, Human/*prevention & control
MH  - Orthomyxoviridae/*immunology
MH  - Pregnancy
MH  - Vaccines, Attenuated/adverse effects
EDAT- 2010/10/23 06:00
MHDA- 2011/03/15 06:00
CRDT- 2010/10/23 06:00
PHST- 2010/06/08 00:00 [received]
PHST- 2010/08/13 00:00 [revised]
PHST- 2010/08/30 00:00 [accepted]
PHST- 2010/10/23 06:00 [entrez]
PHST- 2010/10/23 06:00 [pubmed]
PHST- 2011/03/15 06:00 [medline]
AID - S0002-9378(10)01105-1 [pii]
AID - 10.1016/j.ajog.2010.08.050 [doi]
PST - ppublish
SO  - Am J Obstet Gynecol. 2011 Feb;204(2):146.e1-7. doi: 10.1016/j.ajog.2010.08.050. 
      Epub 2010 Oct 20.