PMID- 20967485
OWN - NLM
STAT- MEDLINE
DCOM- 20110428
LR  - 20211020
IS  - 1573-2630 (Electronic)
IS  - 0165-5701 (Linking)
VI  - 31
IP  - 1
DP  - 2011 Feb
TI  - Eyelid and conjunctival paracoccidioidomycosis simulating carcinoma.
PG  - 63-7
LID - 10.1007/s10792-010-9407-7 [doi]
AB  - Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis in 
      immunocompetent individuals in Brazil. Ocular infection by PCM is rare; however, 
      when infection does occur, the most common ocular sites involved are eyelid and 
      conjunctiva. A 68-year-old white male presented with a 2-month history of a 
      painless, ulcerated, infiltrative and diffuse whitish lesion located on the right 
      inferior eyelid. A clinical diagnosis of malignant tumor, possibly squamous cell 
      carcinoma, was made. The histopathologic examination showed a hyperplastic 
      epithelium with inflammatory infiltrate of lymphocytes, plasma cells, neutrophils 
      and histiocytes. Large numbers of giant cells were also present. Periodic acid 
      Schiff and Grocott (silver methenamine) stains showed several large round 
      structures with peripheral lateral small budding cells that resembled a "ship's 
      wheel". No multinucleated fungi were seen. The fungi varied in size and small 
      forms were round and single fungal structures. A diagnosis of 
      paracoccidioidomycosis was made PCM eyelid infection is rare and can simulate 
      carcinoma both clinically and histopathologically.
FAU - Odashiro, Alexandre N
AU  - Odashiro AN
AD  - Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil. 
      alexandrenakao@yahoo.com.br
FAU - Odashiro, Patricia R P
AU  - Odashiro PR
FAU - Fernandes, Priscila I
AU  - Fernandes PI
FAU - Leite, Livio V O
AU  - Leite LV
FAU - Odashiro, Macanori
AU  - Odashiro M
FAU - Maloney, Shawn
AU  - Maloney S
FAU - Fernandes, Bruno F
AU  - Fernandes BF
FAU - Di Cesare, Sebastian
AU  - Di Cesare S
FAU - Burnier, Miguel N Jr
AU  - Burnier MN Jr
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20101022
PL  - Netherlands
TA  - Int Ophthalmol
JT  - International ophthalmology
JID - 7904294
SB  - IM
MH  - Aged
MH  - Carcinoma, Squamous Cell/*diagnosis
MH  - Conjunctival Diseases/*diagnosis
MH  - Diagnosis, Differential
MH  - Eye Infections, Fungal/*diagnosis
MH  - Eye Neoplasms
MH  - Eyelid Diseases/*diagnosis
MH  - Humans
MH  - Male
MH  - *Paracoccidioides
MH  - Paracoccidioidomycosis/*diagnosis
EDAT- 2010/10/23 06:00
MHDA- 2011/04/29 06:00
CRDT- 2010/10/23 06:00
PHST- 2010/01/03 00:00 [received]
PHST- 2010/09/23 00:00 [accepted]
PHST- 2010/10/23 06:00 [entrez]
PHST- 2010/10/23 06:00 [pubmed]
PHST- 2011/04/29 06:00 [medline]
AID - 10.1007/s10792-010-9407-7 [doi]
PST - ppublish
SO  - Int Ophthalmol. 2011 Feb;31(1):63-7. doi: 10.1007/s10792-010-9407-7. Epub 2010 
      Oct 22.