PMID- 20970769 OWN - NLM STAT- MEDLINE DCOM- 20110121 LR - 20220409 IS - 1879-1891 (Electronic) IS - 0002-9394 (Linking) VI - 151 IP - 1 DP - 2011 Jan TI - Axial length and outcomes of macular hole surgery assessed by spectral-domain optical coherence tomography. PG - 118-127.e1 LID - 10.1016/j.ajo.2010.07.007 [doi] AB - PURPOSE: To use spectral-domain optical coherence tomography (SD OCT) to evaluate macular hole surgery outcomes and features predicting anatomic failure. DESIGN: Retrospective, interventional case series. METHODS: Fifty-two eyes of 50 consecutive patients with macular holes were examined. All eyes underwent 3-port pars plana vitrectomy with internal limiting membrane peeling. Eyes were examined after surgery by dense serial SD OCT scanning over the macula. RESULTS: Eyes with initial anatomic failure were significantly more likely to have greater axial length and refractive error and more posterior staphyloma compared with eyes with initial anatomic success (P = .031 to .0060, < .0001). Overall initial and final anatomic success rates were 92.3% (48 of 52 eyes). In highly myopic eyes with axial lengths of 26.0 mm or more, initial and final success rates were 73.3% (11 of 15 eyes) compared with 100.0% (37 of 37 eyes) of eyes with axial lengths of less than 26.0 mm (P = .0050). In highly myopic eyes, initial and final success rates were 0% (0 of 3 eyes) of eyes with axial lengths of 30.0 mm or more compared with 91.7% (11 of 12 eyes) of eyes with axial lengths of 26.0 mm or more and of less than 30.0 mm (P < .0001). Retinoschisis-like thickening of the outer retina was seen in 3 (75.0%) of 4 eyes with initial failure compared with 3 (6.3%) of 48 eyes with initial success (P = .0030). CONCLUSIONS: Axial length of 30.0 mm or more may increase the risk of anatomic failure of macular hole surgery. CI - Copyright (c) 2011 Elsevier Inc. All rights reserved. FAU - Suda, Kenji AU - Suda K AD - Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Japan. FAU - Hangai, Masanori AU - Hangai M FAU - Yoshimura, Nagahisa AU - Yoshimura N LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Am J Ophthalmol JT - American journal of ophthalmology JID - 0370500 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Axial Length, Eye/*pathology MH - Basement Membrane/surgery MH - Female MH - Humans MH - Male MH - Middle Aged MH - Prone Position MH - Retinal Perforations/*diagnosis/*surgery MH - Retrospective Studies MH - *Tomography, Optical Coherence MH - Tonometry, Ocular MH - Treatment Outcome MH - Visual Acuity/physiology MH - *Vitrectomy EDAT- 2010/10/26 06:00 MHDA- 2011/01/22 06:00 CRDT- 2010/10/26 06:00 PHST- 2010/02/19 00:00 [received] PHST- 2010/07/06 00:00 [revised] PHST- 2010/07/09 00:00 [accepted] PHST- 2010/10/26 06:00 [entrez] PHST- 2010/10/26 06:00 [pubmed] PHST- 2011/01/22 06:00 [medline] AID - S0002-9394(10)00533-7 [pii] AID - 10.1016/j.ajo.2010.07.007 [doi] PST - ppublish SO - Am J Ophthalmol. 2011 Jan;151(1):118-127.e1. doi: 10.1016/j.ajo.2010.07.007.