PMID- 20977844
OWN - NLM
STAT- MEDLINE
DCOM- 20120126
LR  - 20101027
IS  - 1003-0603 (Print)
IS  - 1003-0603 (Linking)
VI  - 22
IP  - 10
DP  - 2010 Oct
TI  - [A study of the influence of the guideline on the treatment of chronic congestive 
      heart failure in the elderly].
PG  - 606-9
AB  - OBJECTIVE: To investigate the changes in drug treatment in elderly inpatients 
      with chronic congestive heart failure (CHF) after the publication of the 
      guideline. METHODS: Three thousands one hundred and seventy-four hospitalized 
      patients over 60 years old with CHF admitted from January 1990 to July 2007 to 
      Second Hospital of Tianjin Medical University were enrolled, and the patients 
      were divided into three groups according to every 6 years by the time when 
      guideline of the American College of Cardiology/American Heart Association 
      (ACC/AHA) was published. The changes in drug treatment were analyzed 
      retrospectively. RESULTS: The proportion of enrolled patients was 79.2% (3 174/4 
      010) of total number of CHF patients. The number of male patients was 1 639, and 
      that of the female 1 535. The age ranged 60-98 years old with the mean age 
      (71.94+/-7.07) years old. Three groups were from 1990 to 1995 (group A), from 1996 
      to 2001 (group B) and from 2002 to 2007 (group C) respectively. The patients' age 
      (years old) of three groups increased year by year (mean age of each group was 
      68.99+/-6.71, 71.56+/-6.86, 73.79+/-7.01 respectively, F=91.142, P<0.01). The three 
      major causes of heart failure were coronary heart disease (55.3%, 64.5%, 81.8%), 
      pulmonary heart disease (21.9%, 19.3%,5.5%) and rheumatic heart disease (16.5%, 
      10.3%, 7.5%). The difference among the three causes was statistically significant 
      (chi(2)=217.979, P<0.01 ). Cardiac function on admission was mostly New York Heart 
      Association (NYHA) grade III or IV (1 561 cases of NYHA III, 1 433 cases of NYHA 
      IV, chi(2)=75.828, P<0.01 ). The outcome was mostly improved (the proportion of 
      three groups was 88.9%, 88.3%, 92.7%, respectively, chi(2)=35.002, P<0.01). The 
      frequency of using nitrate esters, beta-blocker, angiotensin receptor blocker (ARB), 
      aldosterone antagonist was increased year by year (all P<0.05). The use of 
      digitalis was decreased gradually (both P<0.05). The angiotensin converting 
      enzyme inhibitor (ACEI) and beta-blocker were mostly used in coronary heart disease, 
      and their frequency was 81.3% (1 698/2 088) and 87.8% (768/875) respectively. 
      CONCLUSION: The guidelines made positive effects on the treatment of elderly 
      inpatients with CHF. The treatment drugs that can improve the prognosis of CHF 
      should be used in this group in time.
FAU - Liu, Jian
AU  - Liu J
AD  - Department of Emergency, Second Hospital of Tianjin Medical University, Tianjin 
      300211, China.
FAU - Ma, Jin-Ping
AU  - Ma JP
FAU - Huang, Jiao-Hong
AU  - Huang JH
FAU - Wang, Lin
AU  - Wang L
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
JT  - Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo 
      weizhongbing jijiuyixue
JID - 9887521
RN  - 0 (Adrenergic beta-Antagonists)
RN  - 0 (Angiotensin Receptor Antagonists)
RN  - 0 (Angiotensin-Converting Enzyme Inhibitors)
SB  - IM
MH  - Adrenergic beta-Antagonists/therapeutic use
MH  - Aged
MH  - Aged, 80 and over
MH  - American Heart Association
MH  - Angiotensin Receptor Antagonists/therapeutic use
MH  - Angiotensin-Converting Enzyme Inhibitors/therapeutic use
MH  - Chronic Disease
MH  - Female
MH  - Heart Failure/*drug therapy
MH  - Humans
MH  - Inpatients
MH  - Male
MH  - Middle Aged
MH  - *Practice Guidelines as Topic
MH  - Retrospective Studies
MH  - United States
EDAT- 2010/10/28 06:00
MHDA- 2012/01/27 06:00
CRDT- 2010/10/28 06:00
PHST- 2010/10/28 06:00 [entrez]
PHST- 2010/10/28 06:00 [pubmed]
PHST- 2012/01/27 06:00 [medline]
PST - ppublish
SO  - Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2010 Oct;22(10):606-9.