PMID- 20978814 OWN - NLM STAT- MEDLINE DCOM- 20110315 LR - 20211020 IS - 1435-4373 (Electronic) IS - 0934-9723 (Print) IS - 0934-9723 (Linking) VI - 30 IP - 1 DP - 2011 Jan TI - Improvement of attention span and reaction time with hyperbaric oxygen treatment in patients with toxic injury due to mold exposure. PG - 1-6 LID - 10.1007/s10096-010-0937-8 [doi] AB - It is, by now, well established that mold toxins (mycotoxins) can cause significant adverse health effects. In this study, 15 subjects who developed an attention deficit disorder (ADD) and slowing of reaction time at the time of exposure to mold toxins were identified. Deficits in attention span and reaction time were documented not only by taking a careful history, but also by performing a Test of Variables of Attention (TOVA). The TOVA test provides an objective measure of these two variables. It was found that mold-exposed subjects show statistically significant decreases in attention span and significant increases in reaction time to stimuli compared to controls. After ten sessions of hyperbaric oxygen treatment (HBOT), a statistically significant improvement was seen in both measures. This preliminary study suggests promising outcomes in treating mold-exposed patients with hyperbaric oxygen. FAU - Ezra, N AU - Ezra N AD - Department of Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA. FAU - Dang, K AU - Dang K FAU - Heuser, G AU - Heuser G LA - eng PT - Journal Article DEP - 20101027 PL - Germany TA - Eur J Clin Microbiol Infect Dis JT - European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology JID - 8804297 SB - IM MH - Adolescent MH - Adult MH - Attention/*drug effects MH - Attention Deficit Disorder with Hyperactivity/*drug therapy MH - Fungi/*isolation & purification MH - Humans MH - Hyperbaric Oxygenation/*methods MH - Middle Aged MH - Mycoses/*complications/*drug therapy/microbiology MH - Reaction Time/*drug effects MH - Treatment Outcome MH - Young Adult PMC - PMC2998645 EDAT- 2010/10/28 06:00 MHDA- 2011/03/16 06:00 PMCR- 2010/10/27 CRDT- 2010/10/28 06:00 PHST- 2009/11/29 00:00 [received] PHST- 2010/04/03 00:00 [accepted] PHST- 2010/10/28 06:00 [entrez] PHST- 2010/10/28 06:00 [pubmed] PHST- 2011/03/16 06:00 [medline] PHST- 2010/10/27 00:00 [pmc-release] AID - 937 [pii] AID - 10.1007/s10096-010-0937-8 [doi] PST - ppublish SO - Eur J Clin Microbiol Infect Dis. 2011 Jan;30(1):1-6. doi: 10.1007/s10096-010-0937-8. Epub 2010 Oct 27.