PMID- 20979625
OWN - NLM
STAT- MEDLINE
DCOM- 20110131
LR  - 20211020
IS  - 1743-422X (Electronic)
IS  - 1743-422X (Linking)
VI  - 7
DP  - 2010 Oct 27
TI  - Molecular characterization of porcine circovirus 2 isolated from diseased pigs 
      co-infected with porcine reproductive and respiratory syndrome virus.
PG  - 286
LID - 10.1186/1743-422X-7-286 [doi]
AB  - In this study, we isolated a porcine circovirus 2 (PCV2) strain from piglets 
      co-infected with porcine reproductive and respiratory syndrome virus (PRRSV). The 
      complete genome of this strain was sequenced, phylogenetic and polymorphic 
      analyses were carried out. BLAST searches revealed the highest sequence identity 
      (99.5% nt and 99.3% aa) to Guangxi strain EF675230. The phylogenetic tree showed 
      that clustering of the isolates didn't strongly correlate to geographical 
      distribution. Polymorphic analyses demonstrated that the amino acids at most of 
      the polymorphic sites in Open Reading Frame 1(ORF1) and 2 (ORF2)belong to the 
      same amino acid group according to chemical or structural properties, and 
      revealed that highly polymorphic regions overlapped with the known immunoreactive 
      epitopes of ORF2.
FAU - Yi, Jianzhong
AU  - Yi J
AD  - Institute of Animal Husbandry Veterinary Sciences, Shanghai Academy of 
      Agricultural Sciences, 2901 Beidi Road, Shanghai 201106, PR China. 
      yijianzhong@yahoo.com
FAU - Liu, Chengqian
AU  - Liu C
LA  - eng
SI  - GENBANK/GU124593
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20101027
PL  - England
TA  - Virol J
JT  - Virology journal
JID - 101231645
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Animals
MH  - Circoviridae Infections/*veterinary/virology
MH  - Circovirus/*genetics/*isolation & purification
MH  - Cluster Analysis
MH  - DNA, Viral/chemistry/genetics
MH  - Genome, Viral
MH  - Molecular Sequence Data
MH  - Open Reading Frames
MH  - Phylogeny
MH  - Polymorphism, Genetic
MH  - Porcine Reproductive and Respiratory Syndrome/*virology
MH  - Porcine respiratory and reproductive syndrome virus
MH  - Sequence Analysis, DNA
MH  - Sequence Homology
MH  - Swine
MH  - Swine Diseases/*virology
PMC - PMC2988019
EDAT- 2010/10/29 06:00
MHDA- 2011/02/01 06:00
PMCR- 2010/10/27
CRDT- 2010/10/29 06:00
PHST- 2010/09/13 00:00 [received]
PHST- 2010/10/27 00:00 [accepted]
PHST- 2010/10/29 06:00 [entrez]
PHST- 2010/10/29 06:00 [pubmed]
PHST- 2011/02/01 06:00 [medline]
PHST- 2010/10/27 00:00 [pmc-release]
AID - 1743-422X-7-286 [pii]
AID - 10.1186/1743-422X-7-286 [doi]
PST - epublish
SO  - Virol J. 2010 Oct 27;7:286. doi: 10.1186/1743-422X-7-286.