PMID- 20981629
OWN - NLM
STAT- MEDLINE
DCOM- 20110802
LR  - 20120326
IS  - 1747-0927 (Electronic)
IS  - 1747-0919 (Linking)
VI  - 5
IP  - 5-6
DP  - 2010
TI  - Age-related valence-based reversal in recruitment of medial prefrontal cortex on 
      a visual search task.
PG  - 560-76
LID - 10.1080/17470910903512296 [doi]
AB  - Previous behavioral research has revealed a positivity effect that occurs with 
      aging, with older adults focusing more on positive information and less on 
      negative emotional stimuli as compared to young adults. Questions have been 
      raised as to whether this effect exists in the rapid detection of information or 
      whether it operates only at later stages of processing. In the present study, we 
      used eye-tracking and neuroimaging methodologies to examine whether the two age 
      groups accomplished the detection of emotional information on a visual search 
      task using the same mechanisms. Eye-tracking results revealed no significant age 
      differences in detection or viewing time of emotional targets as a function of 
      valence. Despite their general similarity in task performance, neuroimaging 
      results revealed an age-related valence-based reversal in medial prefrontal 
      cortex (MPFC) activity, with detection of negative compared to positive targets 
      activating the MPFC more for younger adults, and detection of positive compared 
      to negative targets activating the MPFC more for older adults. These results 
      suggest that age-related valence reversals in neural activity can exist even on 
      tasks that require only relatively automatic processing of emotional information.
CI  - (c) 2010 Psychology Press
FAU - Leclerc, Christina M
AU  - Leclerc CM
AD  - Department of Psychology, Boston College, McGuinn Hall, Room 512, 140 
      Commonwealth Ave., Chestnut Hill, MA 02467, USA. christina.leclerc.1@bc.edu
FAU - Kensinger, Elizabeth A
AU  - Kensinger EA
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - England
TA  - Soc Neurosci
JT  - Social neuroscience
JID - 101279009
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Aging/*physiology/*psychology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Photic Stimulation/*methods
MH  - Prefrontal Cortex/*physiology
MH  - Psychomotor Performance/physiology
MH  - Reaction Time/physiology
MH  - Visual Perception/*physiology
MH  - Young Adult
EDAT- 2010/10/29 06:00
MHDA- 2011/08/04 06:00
CRDT- 2010/10/29 06:00
PHST- 2010/10/29 06:00 [entrez]
PHST- 2010/10/29 06:00 [pubmed]
PHST- 2011/08/04 06:00 [medline]
AID - 927980293 [pii]
AID - 10.1080/17470910903512296 [doi]
PST - ppublish
SO  - Soc Neurosci. 2010;5(5-6):560-76. doi: 10.1080/17470910903512296.