PMID- 21034724
OWN - NLM
STAT- MEDLINE
DCOM- 20101228
LR  - 20211020
IS  - 1090-2104 (Electronic)
IS  - 0006-291X (Print)
IS  - 0006-291X (Linking)
VI  - 402
IP  - 3
DP  - 2010 Nov 19
TI  - Adipose tissue-derived stem cells secrete CXCL5 cytokine with chemoattractant and 
      angiogenic properties.
PG  - 560-4
LID - 10.1016/j.bbrc.2010.10.090 [doi]
AB  - Adipose tissue-derived stem cells (ADSC) secreted CXCL5 cytokine abundantly and 
      higher passaged ADSC up to passage 6 (P6) secreted more CXCL5 than lower passaged 
      ADSC. Higher passaged ADSC also appeared to express higher levels of CXCL5 
      receptor, i.e., CXCR2. Both CXCL5 and CXCR2 were localized in the tunica intima 
      and tunica adventitia of blood vessels in adipose tissue. Colocalization with 
      CD34 further indicates their association with the putative ADSC in tunica 
      adventitia. Migration assay indicates chemoattractant effects of CXCL5 on ADSC 
      and HUVEC endothelial cells. CXCL5 also enhanced matrigel-based endothelial 
      tube-like formation of HUVEC.
CI  - Copyright (c) 2010 Elsevier Inc. All rights reserved.
FAU - Zhang, Haiyang
AU  - Zhang H
AD  - Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, 
      University of California, San Francisco, CA 94143-0738, USA.
FAU - Ning, Hongxiu
AU  - Ning H
FAU - Banie, Lia
AU  - Banie L
FAU - Wang, Guifang
AU  - Wang G
FAU - Lin, Guiting
AU  - Lin G
FAU - Lue, Tom F
AU  - Lue TF
FAU - Lin, Ching-Shwun
AU  - Lin CS
LA  - eng
GR  - DK069655/DK/NIDDK NIH HHS/United States
GR  - DK045370/DK/NIDDK NIH HHS/United States
GR  - DK64538/DK/NIDDK NIH HHS/United States
GR  - R01 DK069655/DK/NIDDK NIH HHS/United States
GR  - P50 DK064538/DK/NIDDK NIH HHS/United States
GR  - R37 DK045370/DK/NIDDK NIH HHS/United States
GR  - R01 DK045370/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20101027
PL  - United States
TA  - Biochem Biophys Res Commun
JT  - Biochemical and biophysical research communications
JID - 0372516
RN  - 0 (CXCL5 protein, human)
RN  - 0 (Chemokine CXCL5)
RN  - 0 (Receptors, Interleukin-8B)
SB  - IM
MH  - Adipose Tissue/cytology/*metabolism
MH  - Capillaries/growth & development
MH  - Cell Movement
MH  - Cells, Cultured
MH  - Chemokine CXCL5/*metabolism
MH  - Endothelium, Vascular/cytology/*metabolism
MH  - Humans
MH  - *Neovascularization, Physiologic
MH  - Receptors, Interleukin-8B/metabolism
MH  - Stem Cells/*metabolism
MH  - Tunica Intima/cytology/metabolism
PMC - PMC3530412
MID - NIHMS249255
EDAT- 2010/11/03 06:00
MHDA- 2010/12/29 06:00
PMCR- 2012/12/26
CRDT- 2010/11/02 06:00
PHST- 2010/10/12 00:00 [received]
PHST- 2010/10/20 00:00 [accepted]
PHST- 2010/11/02 06:00 [entrez]
PHST- 2010/11/03 06:00 [pubmed]
PHST- 2010/12/29 06:00 [medline]
PHST- 2012/12/26 00:00 [pmc-release]
AID - S0006-291X(10)01979-0 [pii]
AID - 10.1016/j.bbrc.2010.10.090 [doi]
PST - ppublish
SO  - Biochem Biophys Res Commun. 2010 Nov 19;402(3):560-4. doi: 
      10.1016/j.bbrc.2010.10.090. Epub 2010 Oct 27.