PMID- 21042441
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20211020
IS  - 1998-3808 (Electronic)
IS  - 0971-3026 (Print)
IS  - 0970-2016 (Linking)
VI  - 20
IP  - 3
DP  - 2010 Aug
TI  - Case report: MR spectroscopy in pantothenate kinase-2 associated 
      neurodegeneration.
PG  - 188-91
LID - 10.4103/0971-3026.69353 [doi]
AB  - We report a case of a 13-year-old girl with Hallervorden-Spatz disease (HSD) or 
      pantothenate kinase-2 associated neurodegeneration (PKAN). HSD is a rare 
      neurodegenerative disorder, which is characterized by a rapidly progressive 
      extrapyramidal syndrome, dementia with optic atrophy, and retinal degeneration. 
      It is associated with accumulation of cysteine-iron complex in the globus pallidi 
      and substantia nigra. The MRI "eye of the tiger" sign is the characteristic. MRI 
      spectroscopy is also characteristic. It shows markedly decreased NAA/Cr values in 
      the globus pallidi and substantia nigra with increased mI/Cr values that suggest 
      of gliosis.
FAU - Parashari, Umesh C
AU  - Parashari UC
AD  - Department of Radio Diagnosis, C.S.M. Medical University, (Upgraded K.G. Medical 
      University) Lucknow, UP, India.
FAU - Aga, Pallavi
AU  - Aga P
FAU - Parihar, Anit
AU  - Parihar A
FAU - Singh, Ragini
AU  - Singh R
FAU - Joshi, Vindhya
AU  - Joshi V
LA  - eng
PT  - Case Reports
PL  - Germany
TA  - Indian J Radiol Imaging
JT  - The Indian journal of radiology & imaging
JID - 8503873
PMC - PMC2963751
OTO - NOTNLM
OT  - Basal ganglia
OT  - Hallervorden-Spatz disease
OT  - PKAN
OT  - dystonia
OT  - iron deposition
OT  - magnetic resonance spectroscopy
COIS- Conflict of Interest: None declared.
EDAT- 2010/11/03 06:00
MHDA- 2010/11/03 06:01
PMCR- 2010/08/01
CRDT- 2010/11/03 06:00
PHST- 2010/11/03 06:00 [entrez]
PHST- 2010/11/03 06:00 [pubmed]
PHST- 2010/11/03 06:01 [medline]
PHST- 2010/08/01 00:00 [pmc-release]
AID - IJRI-20-188 [pii]
AID - 10.4103/0971-3026.69353 [doi]
PST - ppublish
SO  - Indian J Radiol Imaging. 2010 Aug;20(3):188-91. doi: 10.4103/0971-3026.69353.