PMID- 21051598
OWN - NLM
STAT- MEDLINE
DCOM- 20101223
LR  - 20240417
IS  - 1095-9203 (Electronic)
IS  - 0036-8075 (Print)
IS  - 0036-8075 (Linking)
VI  - 330
IP  - 6010
DP  - 2010 Dec 10
TI  - The major genetic determinants of HIV-1 control affect HLA class I peptide 
      presentation.
PG  - 1551-7
LID - 10.1126/science.1195271 [doi]
AB  - Infectious and inflammatory diseases have repeatedly shown strong genetic 
      associations within the major histocompatibility complex (MHC); however, the 
      basis for these associations remains elusive. To define host genetic effects on 
      the outcome of a chronic viral infection, we performed genome-wide association 
      analysis in a multiethnic cohort of HIV-1 controllers and progressors, and we 
      analyzed the effects of individual amino acids within the classical human 
      leukocyte antigen (HLA) proteins. We identified >300 genome-wide significant 
      single-nucleotide polymorphisms (SNPs) within the MHC and none elsewhere. 
      Specific amino acids in the HLA-B peptide binding groove, as well as an 
      independent HLA-C effect, explain the SNP associations and reconcile both 
      protective and risk HLA alleles. These results implicate the nature of the 
      HLA-viral peptide interaction as the major factor modulating durable control of 
      HIV infection.
CN  - International HIV Controllers Study
AD  - Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of 
      Technology (MIT) and Harvard, Boston, MA, USA.
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AU  - Lian J
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AU  - Cafaro V
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AU  - Conway B
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AU  - Cornelson B
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AU  - Cox DT
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AU  - Cuchural G Jr
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AU  - Fuller JD
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AU  - Gaberman J
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AU  - Garcia E
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AU  - Garmon D
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AU  - Gathe JC Jr
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AU  - Gilson I
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AU  - Goepfert PA
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AU  - Goulston C
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AU  - Groger RK
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AU  - Gurley TD
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AU  - Haber S
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AU  - Hardwicke R
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AU  - Hardy WD
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AU  - Harrigan PR
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AU  - Hawkins TN
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AU  - Heath S
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AU  - Hecht FM
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AU  - Henry WK
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AU  - Hladek M
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AU  - Hoffman RP
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AU  - Horton JM
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AU  - Hsu RK
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AU  - Huhn GD
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AU  - Hunt P
FAU - Hupert, Mark J
AU  - Hupert MJ
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AU  - Illeman ML
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AU  - Jaeger H
FAU - Jellinger, Robert M
AU  - Jellinger RM
FAU - John, Mina
AU  - John M
FAU - Johnson, Jennifer A
AU  - Johnson JA
FAU - Johnson, Kristin L
AU  - Johnson KL
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AU  - Johnson H
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AU  - Johnson K
FAU - Joly, Jennifer
AU  - Joly J
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AU  - Jordan WC
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AU  - Kauffman CA
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AU  - Khanlou H
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AU  - Killian RK
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AU  - Kim AY
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AU  - Kim DD
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AU  - Kinder CA
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AU  - Kirchner JT
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AU  - Kogelman L
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AU  - Kojic EM
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AU  - Korthuis PT
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AU  - Kurisu W
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AU  - Kwon DS
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AU  - LaMar M
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AU  - Lampiris H
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AU  - Lanzafame M
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AU  - Lederman MM
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AU  - Lee DM
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AU  - Lee JM
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AU  - Lee MJ
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AU  - Lee ET
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AU  - Lemoine J
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AU  - Levy JA
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AU  - Llibre JM
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AU  - Liguori MA
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AU  - Little SJ
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AU  - Liu AY
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AU  - Lopez AJ
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AU  - Loutfy MR
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AU  - Loy D
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AU  - Mohammed DY
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AU  - Man A
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AU  - Mansour MK
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AU  - Marconi VC
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AU  - Markowitz M
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AU  - Marques R
FAU - Martin, Jeffrey N
AU  - Martin JN
FAU - Martin, Harold L Jr
AU  - Martin HL Jr
FAU - Mayer, Kenneth Hugh
AU  - Mayer KH
FAU - McElrath, M Juliana
AU  - McElrath MJ
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AU  - McGhee TA
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AU  - McGovern BH
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AU  - McGowan K
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AU  - McIntyre D
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AU  - Mcleod GX
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AU  - Menezes P
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AU  - Mesa G
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AU  - Metroka CE
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AU  - Meyer-Olson D
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AU  - Miller AO
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AU  - Montgomery K
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AU  - Mounzer KC
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AU  - Nagami EH
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AU  - Nahass RG
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AU  - Nelson MO
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AU  - Nielsen C
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AU  - Norene DL
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AU  - O'Connor DH
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AU  - Ojikutu BO
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AU  - Okulicz J
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AU  - Oladehin OO
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AU  - Oldfield EC 3rd
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AU  - Olender SA
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AU  - Ostrowski M
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AU  - Owen WF Jr
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AU  - Pae E
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AU  - Parsonnet J
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AU  - Pavlatos AM
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AU  - Perlmutter AM
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AU  - Pierce MN
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AU  - Pincus JM
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AU  - Pisani L
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AU  - Price LJ
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AU  - Proia L
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AU  - Prokesch RC
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AU  - Pujet HC
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AU  - Ramgopal M
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AU  - Rathod A
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AU  - Rausch M
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AU  - Ravishankar J
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AU  - Rhame FS
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AU  - Richards CS
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AU  - Richman DD
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AU  - Rodes B
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AU  - Rodriguez M
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AU  - Rose RC 3rd
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AU  - Rosenberg ES
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AU  - Rosenthal D
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AU  - Ross PE
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AU  - Rubin DS
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AU  - Saenz L
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AU  - Salvaggio MR
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AU  - Sanchez WC
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AU  - Sanjana VM
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AU  - Santiago S
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AU  - Schmidt W
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AU  - Schuitemaker H
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AU  - Sestak PM
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AU  - Shalit P
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AU  - Shay W
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AU  - Shirvani VN
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AU  - Silebi VI
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AU  - Sizemore JM Jr
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AU  - Skolnik PR
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AU  - Sokol-Anderson M
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AU  - Stabile P
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AU  - Stapleton JT
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AU  - Starrett S
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AU  - Stein F
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AU  - Stellbrink HJ
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AU  - Sterman FL
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AU  - Stone VE
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AU  - Stone DR
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AU  - Tambussi G
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AU  - Taplitz RA
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AU  - Tedaldi EM
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AU  - Telenti A
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AU  - Theisen W
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AU  - Torres R
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AU  - Tosiello L
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AU  - Tremblay C
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AU  - Tribble MA
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AU  - Vaccaro A
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GR  - U01 AI069513-05/AI/NIAID NIH HHS/United States
GR  - U01 AI069465-05/AI/NIAID NIH HHS/United States
GR  - AI069513/AI/NIAID NIH HHS/United States
GR  - AI069502/AI/NIAID NIH HHS/United States
GR  - K24 AI069994/AI/NIAID NIH HHS/United States
GR  - TL1 RR024978/RR/NCRR NIH HHS/United States
GR  - AI069423/AI/NIAID NIH HHS/United States
GR  - U01 AI069419-05/AI/NIAID NIH HHS/United States
GR  - AI30914/AI/NIAID NIH HHS/United States
GR  - U01 AI069428/AI/NIAID NIH HHS/United States
GR  - U01 AI069532/AI/NIAID NIH HHS/United States
GR  - K24 AI051966/AI/NIAID NIH HHS/United States
GR  - KL2 RR024977/RR/NCRR NIH HHS/United States
GR  - U01 AI069467-05/AI/NIAID NIH HHS/United States
GR  - UL1 RR024131/RR/NCRR NIH HHS/United States
GR  - U01 AI069484-05/AI/NIAID NIH HHS/United States
GR  - UM1 AI069415/AI/NIAID NIH HHS/United States
GR  - UL1 RR024131-06/RR/NCRR NIH HHS/United States
GR  - AI030914/AI/NIAID NIH HHS/United States
GR  - U01 AI069511-06/AI/NIAID NIH HHS/United States
GR  - P30 AI027763-19/AI/NIAID NIH HHS/United States
GR  - AI27661/AI/NIAID NIH HHS/United States
GR  - U01 AI069452-06/AI/NIAID NIH HHS/United States
GR  - U01 AI069477-05/AI/NIAID NIH HHS/United States
GR  - U01 MH085520-01/MH/NIMH NIH HHS/United States
GR  - U01 AI046370-04/AI/NIAID NIH HHS/United States
GR  - K24 AI069994-04/AI/NIAID NIH HHS/United States
GR  - UM1 AI069484/AI/NIAID NIH HHS/United States
GR  - AI069428/AI/NIAID NIH HHS/United States
GR  - AI34853/AI/NIAID NIH HHS/United States
GR  - UM1 AI068634/AI/NIAID NIH HHS/United States
GR  - MH085520/MH/NIMH NIH HHS/United States
GR  - U01 AI069501/AI/NIAID NIH HHS/United States
GR  - R24 AI067039/AI/NIAID NIH HHS/United States
GR  - P-30 AI27763/AI/NIAID NIH HHS/United States
GR  - U01 AI069423-05/AI/NIAID NIH HHS/United States
GR  - U01 AI069450-05/AI/NIAID NIH HHS/United States
GR  - AI069452/AI/NIAID NIH HHS/United States
GR  - U01 AI069556-05/AI/NIAID NIH HHS/United States
GR  - AI069495/AI/NIAID NIH HHS/United States
GR  - UM1 AI068634-06/AI/NIAID NIH HHS/United States
GR  - U01 AI069556-06/AI/NIAID NIH HHS/United States
GR  - K24 AI069994-05/AI/NIAID NIH HHS/United States
GR  - UM1 AI069477/AI/NIAID NIH HHS/United States
GR  - U01 AI069432/AI/NIAID NIH HHS/United States
GR  - P-30-AI060354/AI/NIAID NIH HHS/United States
GR  - U01 AI038844-04S2/AI/NIAID NIH HHS/United States
GR  - AI069484/AI/NIAID NIH HHS/United States
GR  - AI068636/AI/NIAID NIH HHS/United States
GR  - U01 AI069423-06/AI/NIAID NIH HHS/United States
GR  - R01 AI087145/AI/NIAID NIH HHS/United States
GR  - U01 AI069450/AI/NIAID NIH HHS/United States
GR  - U01 AI069419-06/AI/NIAID NIH HHS/United States
GR  - RR024975/RR/NCRR NIH HHS/United States
GR  - R01 AI077505-05/AI/NIAID NIH HHS/United States
GR  - U01 AI069511-05/AI/NIAID NIH HHS/United States
GR  - U01 AI069424-05/AI/NIAID NIH HHS/United States
GR  - U01 AI046370/AI/NIAID NIH HHS/United States
GR  - U01 AI068636/AI/NIAID NIH HHS/United States
GR  - UM1 AI069474/AI/NIAID NIH HHS/United States
GR  - U01 AI069467-06/AI/NIAID NIH HHS/United States
GR  - U01 AI069495-06/AI/NIAID NIH HHS/United States
GR  - U01 AI069484-06/AI/NIAID NIH HHS/United States
GR  - R24 AI067039-06/AI/NIAID NIH HHS/United States
GR  - U01 AI034853/AI/NIAID NIH HHS/United States
GR  - R37 AI028568/AI/NIAID NIH HHS/United States
GR  - R01 AI087145-01/AI/NIAID NIH HHS/United States
GR  - U01 AI069434-05/AI/NIAID NIH HHS/United States
GR  - UM1 AI069452/AI/NIAID NIH HHS/United States
GR  - U01 AI069428-05/AI/NIAID NIH HHS/United States
GR  - AI069424/AI/NIAID NIH HHS/United States
GR  - AI087145/AI/NIAID NIH HHS/United States
GR  - UM1 AI069496/AI/NIAID NIH HHS/United States
GR  - U01 AI069415/AI/NIAID NIH HHS/United States
GR  - UL1 RR024131-07/RR/NCRR NIH HHS/United States
GR  - U01 AI069428-06/AI/NIAID NIH HHS/United States
GR  - U01 AI038844-04/AI/NIAID NIH HHS/United States
GR  - U01 AI069495/AI/NIAID NIH HHS/United States
GR  - ImNIH/Intramural NIH HHS/United States
GR  - UM1 AI069556/AI/NIAID NIH HHS/United States
GR  - P30 AI027763/AI/NIAID NIH HHS/United States
GR  - U01 AI038844-04S3/AI/NIAID NIH HHS/United States
GR  - U01 AI069511/AI/NIAID NIH HHS/United States
GR  - U01 AI069432-06/AI/NIAID NIH HHS/United States
GR  - K23 DA019809/DA/NIDA NIH HHS/United States
GR  - UM1 AI068636-07/AI/NIAID NIH HHS/United States
GR  - U01 AI069532-06/AI/NIAID NIH HHS/United States
GR  - U01 AI069502-05/AI/NIAID NIH HHS/United States
GR  - U01 AI069532-05/AI/NIAID NIH HHS/United States
GR  - U01 AI038844-04S1/AI/NIAID NIH HHS/United States
GR  - R01 MH071205/MH/NIMH NIH HHS/United States
GR  - UM1 AI069502/AI/NIAID NIH HHS/United States
GR  - UM1 AI069450/AI/NIAID NIH HHS/United States
GR  - AI34835/AI/NIAID NIH HHS/United States
GR  - U01 AI025859/AI/NIAID NIH HHS/United States
GR  - UM1 AI068636-06/AI/NIAID NIH HHS/United States
GR  - MH071205/MH/NIMH NIH HHS/United States
GR  - UM1 AI069532/AI/NIAID NIH HHS/United States
GR  - R01 MH071205-05/MH/NIMH NIH HHS/United States
GR  - R01 AI087145-02/AI/NIAID NIH HHS/United States
GR  - U01 AI069424/AI/NIAID NIH HHS/United States
GR  - UM1 AI069465/AI/NIAID NIH HHS/United States
GR  - U01 AI032782/AI/NIAID NIH HHS/United States
GR  - UL1 RR024975/RR/NCRR NIH HHS/United States
GR  - K24 AI064086-05/AI/NIAID NIH HHS/United States
GR  - AI069450/AI/NIAID NIH HHS/United States
GR  - U01 AI034853-12/AI/NIAID NIH HHS/United States
GR  - HHSN261200800001C/RC/CCR NIH HHS/United States
GR  - AI069472/AI/NIAID NIH HHS/United States
GR  - UM1 AI069419/AI/NIAID NIH HHS/United States
GR  - AI28568/AI/NIAID NIH HHS/United States
GR  - U01 AI069471-05/AI/NIAID NIH HHS/United States
GR  - AI069432/AI/NIAID NIH HHS/United States
GR  - P30 AI027763-20/AI/NIAID NIH HHS/United States
GR  - U01 AI069502-06/AI/NIAID NIH HHS/United States
GR  - U01 AI069477/AI/NIAID NIH HHS/United States
GR  - U01 AI069424-06/AI/NIAID NIH HHS/United States
GR  - R01 AI077505-04/AI/NIAID NIH HHS/United States
GR  - UM1 AI068634-07/AI/NIAID NIH HHS/United States
GR  - R01 AI028568/AI/NIAID NIH HHS/United States
GR  - U01 AI069474-06/AI/NIAID NIH HHS/United States
GR  - P30 AI060354/AI/NIAID NIH HHS/United States
GR  - U01 AI069495-05/AI/NIAID NIH HHS/United States
GR  - U01 AI069419/AI/NIAID NIH HHS/United States
GR  - R01 AI030914/AI/NIAID NIH HHS/United States
GR  - AI25859/AI/NIAID NIH HHS/United States
GR  - UM1 AI069511/AI/NIAID NIH HHS/United States
GR  - HHSN261200800001E/CA/NCI NIH HHS/United States
GR  - U01 AI069452/AI/NIAID NIH HHS/United States
GR  - UM1 AI069467/AI/NIAID NIH HHS/United States
GR  - U01 AI027661-18/AI/NIAID NIH HHS/United States
GR  - U01 AI069434-06/AI/NIAID NIH HHS/United States
GR  - AI38844/AI/NIAID NIH HHS/United States
GR  - P30 AI060354-08/AI/NIAID NIH HHS/United States
GR  - U01 AI069432-05/AI/NIAID NIH HHS/United States
GR  - R01 AI030914-16/AI/NIAID NIH HHS/United States
GR  - AI069477/AI/NIAID NIH HHS/United States
GR  - U01 AI069472-05/AI/NIAID NIH HHS/United States
GR  - AI069471/AI/NIAID NIH HHS/United States
GR  - U01 AI069471/AI/NIAID NIH HHS/United States
GR  - U01 AI069472/AI/NIAID NIH HHS/United States
GR  - P30 AI050410/AI/NIAID NIH HHS/United States
GR  - R24 AI106039/AI/NIAID NIH HHS/United States
GR  - U01 AI068634/AI/NIAID NIH HHS/United States
GR  - UM1 AI068636/AI/NIAID NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, N.I.H., Intramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20101104
PL  - United States
TA  - Science
JT  - Science (New York, N.Y.)
JID - 0404511
RN  - 0 (Amino Acids)
RN  - 0 (HIV Antigens)
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-C Antigens)
SB  - IM
CIN - Science. 2010 Dec 10;330(6010):1488-90. PMID: 21148380
MH  - Black or African American/genetics
MH  - Alleles
MH  - Amino Acids/physiology
MH  - *Antigen Presentation
MH  - CD8-Positive T-Lymphocytes/immunology
MH  - Cohort Studies
MH  - Disease Progression
MH  - *Genes, MHC Class I
MH  - Genome-Wide Association Study
MH  - HIV Antigens/immunology
MH  - HIV Infections/ethnology/*genetics/*immunology/virology
MH  - HIV Long-Term Survivors
MH  - *HIV-1/immunology
MH  - HLA-A Antigens/chemistry/genetics/immunology/metabolism
MH  - HLA-B Antigens/chemistry/*genetics/immunology/metabolism
MH  - HLA-C Antigens/chemistry/genetics/immunology/metabolism
MH  - Haplotypes
MH  - Hispanic or Latino/genetics
MH  - Humans
MH  - Immunity, Innate
MH  - Logistic Models
MH  - Models, Molecular
MH  - Polymorphism, Single Nucleotide
MH  - Protein Conformation
MH  - Viral Load
MH  - White People/genetics
PMC - PMC3235490
MID - NIHMS331514
EDAT- 2010/11/06 06:00
MHDA- 2010/12/25 06:00
PMCR- 2011/12/11
CRDT- 2010/11/06 06:00
PHST- 2010/11/06 06:00 [entrez]
PHST- 2010/11/06 06:00 [pubmed]
PHST- 2010/12/25 06:00 [medline]
PHST- 2011/12/11 00:00 [pmc-release]
AID - science.1195271 [pii]
AID - 10.1126/science.1195271 [doi]
PST - ppublish
SO  - Science. 2010 Dec 10;330(6010):1551-7. doi: 10.1126/science.1195271. Epub 2010 
      Nov 4.