PMID- 21051826
OWN - NLM
STAT- MEDLINE
DCOM- 20111128
LR  - 20161125
IS  - 1672-7347 (Print)
IS  - 1672-7347 (Linking)
VI  - 35
IP  - 10
DP  - 2010 Oct
TI  - Left ventricular systolic synchrony in dilated cardiomyopathy patients with 
      normal QRS wave.
PG  - 1023-8
LID - 10.3969/j.issn.1672-7347.2010.10.001 [doi]
AB  - OBJECTIVE: To evaluate the distribution characteristics of left ventricular 
      systolic dyssynchrony (LV-SD) in dilated cardiomyopathy (DCM) patients with 
      chronic heart failure (CHF) and normal QRS wave width, by pulsed-wave Doppler 
      tissue imaging (PW-DTI), and study its relation with left ventricular systolic 
      function, ventricular remodeling, and functional mitral regurgitation (FMR). 
      METHODS: The time to peak systolic velocity (Ts) in 12 left ventricular segments 
      was evaluated by PW-DTI, from which the standard deviation (SD) of Ts in the 12 
      segments (Ts-SD) and maximum Ts difference (Ts-maxD) were calculated. RESULTS: 
      Ts-SD and Ts-maxD in the 12 LV segments of the DCM patients with CHF were 
      significantly higher than those of the healthy controls (P<0.01). In DCM patients 
      with CHF and normal QRS wave width, the incidence of LV-SD was 29.8% (14/47) and 
      the inferior wall was the most frequent distribution site of contraction delay. 
      Linear regression analysis revealed a negative correlation between Ts-SD, 
      Ts-maxD, and left ventricular ejection fraction (LVEF) (P<0.01), but a positive 
      correlation between Ts-SD, Ts-maxD and left ventricular end-diastolic volume 
      (LVEDV), lefe ventricular end-systolic volume (LVESV), New York Heart Association 
      (NYHA) cardiac function, FMR (P<0.01) in DCM patients with CHF. CONCLUSION: LV-SD 
      exists in DCM patients with normal QRS width. LV-SD aggravates the LV systolic 
      function damage, which is closely associated with left ventricular remodeling. 
      LV-SD may contribute to the FMR in DCM patients.
FAU - Yi, Na
AU  - Yi N
AD  - Department of Cardiovasology, Xiangya Hospital, Central South University, 
      Changsha 410008, China.
FAU - Zhang, Saidan
AU  - Zhang S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhong Nan Da Xue Xue Bao Yi Xue Ban
JT  - Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. 
      Medical sciences
JID - 101230586
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Cardiomyopathy, Dilated/complications/diagnostic imaging/*physiopathology
MH  - Echocardiography, Doppler, Pulsed/methods
MH  - *Electrocardiography
MH  - Female
MH  - Heart Failure/diagnostic imaging/etiology/*physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Systole
MH  - Ventricular Dysfunction, Left/diagnosis/*physiopathology
MH  - Ventricular Function, Left/*physiology
MH  - Ventricular Remodeling/physiology
MH  - Young Adult
EDAT- 2010/11/06 06:00
MHDA- 2011/12/13 00:00
CRDT- 2010/11/06 06:00
PHST- 2010/11/06 06:00 [entrez]
PHST- 2010/11/06 06:00 [pubmed]
PHST- 2011/12/13 00:00 [medline]
AID - 10.3969/j.issn.1672-7347.2010.10.001 [doi]
PST - ppublish
SO  - Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 Oct;35(10):1023-8. doi: 
      10.3969/j.issn.1672-7347.2010.10.001.