PMID- 21052570 OWN - NLM STAT- MEDLINE DCOM- 20110113 LR - 20191111 IS - 0048-7449 (Print) IS - 0048-7449 (Linking) VI - 62 IP - 3 DP - 2010 Jul-Sep TI - [Polyarthritis flare in patient with ankylosing spondylitis treated with infliximab]. PG - 221-4 AB - Over the last ten years, the treatment of seronegative spondyloarthropathies has changed dramatically with the introduction of the anti-tumor necrosis factor alpha (TNFalpha) agents. Nevertheless, there is a growing number of studies describing several adverse reactions in patients treated with biological agents. In the present report we describe the case of a 22-year-old male patient with ankylosing spondylitis who developed a "paradoxic" adverse reaction, while receiving infliximab. FAU - Gutierrez, M AU - Gutierrez M AD - Clinica Reumatologica, Universita Politecnica delle Marche, Ospedale A. Murri, Jesi (AN), Italia. dr.gmarwin@gmail.com FAU - Becciolini, A AU - Becciolini A FAU - Bertolazzi, C AU - Bertolazzi C FAU - Di Geso, L AU - Di Geso L FAU - Tardella, M AU - Tardella M FAU - Ariani, A AU - Ariani A FAU - Filippucci, E AU - Filippucci E FAU - Grassi, W AU - Grassi W LA - ita PT - Case Reports PT - English Abstract PT - Journal Article TT - Poliartrite febbrile in paziente affetto da spondilite anchilosante in trattamento con infliximab. PL - Italy TA - Reumatismo JT - Reumatismo JID - 0401302 RN - 0 (Antibodies, Monoclonal) RN - 0 (Immunosuppressive Agents) RN - 0 (Tumor Necrosis Factor-alpha) RN - B72HH48FLU (Infliximab) RN - YL5FZ2Y5U1 (Methotrexate) SB - IM MH - Antibodies, Monoclonal/*adverse effects/therapeutic use MH - Arthritis/blood/*chemically induced MH - Fever/chemically induced MH - Humans MH - Immunosuppressive Agents/administration & dosage/*adverse effects/therapeutic use MH - Infliximab MH - Male MH - Methotrexate/administration & dosage/therapeutic use MH - Spondylitis, Ankylosing/blood/*drug therapy MH - Tumor Necrosis Factor-alpha/*antagonists & inhibitors MH - Young Adult EDAT- 2010/11/06 06:00 MHDA- 2011/01/14 06:00 CRDT- 2010/11/06 06:00 PHST- 2010/11/06 06:00 [entrez] PHST- 2010/11/06 06:00 [pubmed] PHST- 2011/01/14 06:00 [medline] AID - 10.4081/reumatismo.2010.221 [doi] PST - ppublish SO - Reumatismo. 2010 Jul-Sep;62(3):221-4. doi: 10.4081/reumatismo.2010.221.