PMID- 21055287 OWN - NLM STAT- MEDLINE DCOM- 20111017 LR - 20101108 IS - 0253-3758 (Print) IS - 0253-3758 (Linking) VI - 38 IP - 7 DP - 2010 Jul TI - [Impact of early catheterization laboratory activation on door-to-balloon time in patients with ST-segment elevation acute myocardial infarction]. PG - 625-8 AB - OBJECTIVE: To determine whether early catheterization laboratory activation would reduce median door-to-balloon time in patients with ST elevation myocardial infarction (STEMI). METHODS: Consecutive patients with STEMI underwent primary percutaneous coronary intervention (PCI) from January 2006 to December 2008 in Beijing Anzhen Hospital were analyzed. Patients were divided into three groups. Group A included patients without prehospital ECG (n = 168), group B included patients with prehospital ECG (n = 224) and group C included patients with prehospital ECG and early telephonic notification to activate catheterization laboratory (n = 114). Primary end point was door-to-balloon time, secondary end points included peak Troponin I elevation, left ventricular ejection fraction, length of hospital stay, hospital mortality and 30 days follow-up mortality. RESULTS: Baseline characteristics were similar among groups. Door-to-balloon time and door-to-catheter laboratory time (110 minutes, 94 minutes and 85 minutes, respectively, all P < 0.01; 91 minutes, 74 minutes and 64 minutes, respectively, all P < 0.01) were significantly shorter in group B and C than those in group A. The percentage of patients with door-to-balloon time less than 90 minutes increased significantly from 32% in group A to 43% in group B and 59% in group C (P < 0.01). CONCLUSION: Early activation of catheterization laboratory by prehospital ECG and telephonic notification could markedly reduce door-to-balloon time in patients with STEMI. FAU - Cheng, Shu-juan AU - Cheng SJ AD - 28th Division, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China. FAU - Yan, Hong-bing AU - Yan HB FAU - Hu, Da-yi AU - Hu DY FAU - Wang, Jian AU - Wang J FAU - Zhao, Han-jun AU - Zhao HJ FAU - Li, Qing-xiang AU - Li QX FAU - Li, Shi-ying AU - Li SY FAU - Zheng, Bin AU - Zheng B FAU - Song, Li AU - Song L FAU - Chi, Yun-peng AU - Chi YP FAU - Wu, Zheng AU - Wu Z LA - chi PT - Controlled Clinical Trial PT - English Abstract PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - China TA - Zhonghua Xin Xue Guan Bing Za Zhi JT - Zhonghua xin xue guan bing za zhi JID - 7910682 SB - IM MH - Aged MH - Angioplasty, Balloon, Coronary MH - Electrocardiography MH - Female MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/*physiopathology/*therapy MH - Time Factors EDAT- 2010/11/09 06:00 MHDA- 2011/10/18 06:00 CRDT- 2010/11/09 06:00 PHST- 2010/11/09 06:00 [entrez] PHST- 2010/11/09 06:00 [pubmed] PHST- 2011/10/18 06:00 [medline] PST - ppublish SO - Zhonghua Xin Xue Guan Bing Za Zhi. 2010 Jul;38(7):625-8.