PMID- 21058018
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110414
LR  - 20160512
IS  - 1618-2650 (Electronic)
IS  - 1618-2642 (Linking)
VI  - 399
IP  - 2
DP  - 2011 Jan
TI  - Dispersive solid-phase extraction for in-sorbent Fourier-transform infrared 
      detection and identification of nerve agent simulants in analysis for 
      verification of chemical weapon convention.
PG  - 955-63
LID - 10.1007/s00216-010-4337-9 [doi]
AB  - The combination of dispersive solid-phase extraction (DSPE) and Fourier-transform 
      infrared (FTIR) spectroscopy is presented for detection and quantification of 
      markers and simulants of nerve agents. Hydrophilic-lipophilic balance (HLB) 
      sorbent was used for extraction and enrichment of organophosphonates from water. 
      When the extraction efficiency of DSPE was compared with that of conventional 
      solid-phase extraction (SPE), DSPE was more efficient. Extraction conditions such 
      as extraction time, and type and quantity of sorbent material were optimized. In 
      DSPE, extracted analytes are detected and quantified on the sorbent using FTIR as 
      analytical technique. Absorbance in FTIR due to P-O-C stretching was used for 
      detection and quantification. Infrared absorbance of different analytes were 
      compared by determining their molar absorptivities (epsilon (max)). Quantitative 
      analyses were performed employing modified Beer's law, and relative standard 
      deviations (RSDs) for intraday repeatability and interday reproducibility were 
      found to be in the range 0.30-0.90% and 0.10-0.80% respectively. The limit of 
      detection (LOD) was 5-10 mug mL(-1). The applicability of the method was tested 
      with an unknown sample prepared by mimicking the sample obtained in an 
      international official proficiency test.
FAU - Garg, Prabhat
AU  - Garg P
AD  - Vertox Laboratory, Defence Research & Development Establishment, Jhansi Road, 
      Gwalior, 474002, India.
FAU - Pardasani, Deepak
AU  - Pardasani D
FAU - Mazumder, Avik
AU  - Mazumder A
FAU - Purohit, Ajay
AU  - Purohit A
FAU - Dubey, D K
AU  - Dubey DK
LA  - eng
PT  - Journal Article
DEP - 20101108
PL  - Germany
TA  - Anal Bioanal Chem
JT  - Analytical and bioanalytical chemistry
JID - 101134327
EDAT- 2010/11/09 06:00
MHDA- 2010/11/09 06:01
CRDT- 2010/11/09 06:00
PHST- 2010/07/29 00:00 [received]
PHST- 2010/10/12 00:00 [accepted]
PHST- 2010/09/17 00:00 [revised]
PHST- 2010/11/09 06:00 [entrez]
PHST- 2010/11/09 06:00 [pubmed]
PHST- 2010/11/09 06:01 [medline]
AID - 10.1007/s00216-010-4337-9 [doi]
PST - ppublish
SO  - Anal Bioanal Chem. 2011 Jan;399(2):955-63. doi: 10.1007/s00216-010-4337-9. Epub 
      2010 Nov 8.