PMID- 21059600
OWN - NLM
STAT- MEDLINE
DCOM- 20110302
LR  - 20101221
IS  - 1469-0756 (Electronic)
IS  - 0032-5473 (Linking)
VI  - 87
IP  - 1023
DP  - 2011 Jan
TI  - Takotsubo cardiomyopathy: a diagnostic challenge.
PG  - 51-9
LID - 10.1136/pgmj.2010.102475 [doi]
AB  - The frequency of the diagnosis of takotsubo cardiomyopathy has increased rapidly 
      over the past few years, possibly due to increasing awareness among 
      cardiologists. At initial presentation the diagnosis remains a challenge because 
      of the close similarity between the presentation of takotsubo cardiomyopathy, and 
      that of ST elevation myocardial infarction (STEMI). Recognition of salient 
      aspects of the medical history at presentation are important in order to organise 
      further appropriate investigations such as echocardiography and left 
      ventriculography at the time of coronary angiogram. Takotsubo cardiomyopathy can 
      be easily missed without ventriculography early after presentation because of the 
      transient nature of left ventricular dysfunction, and in many centres left 
      ventriculogram is not done as standard in the setting of STEMI. The authors 
      advocate left ventriculography in all cases of ST elevation who have unobstructed 
      coronaries. The correct diagnosis of takotsubo cardiomyopathy is very important 
      for future advice and management of the patient. The prognosis of this condition 
      is generally excellent with almost all patients returning to normal within a few 
      weeks. This article examines the takotsubo cardiomyopathy literature and 
      discusses the pathophysiology, clinical features, management, and prognosis of 
      this condition in the context of an illustrated case.
FAU - Zeb, Mehmood
AU  - Zeb M
AD  - Wessex Cardiothoracic Unit, Southampton University Hospitals NHS Trust, 
      Southampton, SO16 6YD, UK. mehmoodzeb@hotmail.com
FAU - Sambu, Nalyaka
AU  - Sambu N
FAU - Scott, Paul
AU  - Scott P
FAU - Curzen, Nick
AU  - Curzen N
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20101107
PL  - England
TA  - Postgrad Med J
JT  - Postgraduate medical journal
JID - 0234135
SB  - IM
MH  - Aged
MH  - Diagnostic Techniques, Cardiovascular
MH  - Electrocardiography
MH  - Female
MH  - Humans
MH  - Prognosis
MH  - Takotsubo Cardiomyopathy/*diagnosis/physiopathology/therapy
EDAT- 2010/11/10 06:00
MHDA- 2011/03/03 06:00
CRDT- 2010/11/10 06:00
PHST- 2010/11/10 06:00 [entrez]
PHST- 2010/11/10 06:00 [pubmed]
PHST- 2011/03/03 06:00 [medline]
AID - pgmj.2010.102475 [pii]
AID - 10.1136/pgmj.2010.102475 [doi]
PST - ppublish
SO  - Postgrad Med J. 2011 Jan;87(1023):51-9. doi: 10.1136/pgmj.2010.102475. Epub 2010 
      Nov 7.