PMID- 21062650
OWN - NLM
STAT- MEDLINE
DCOM- 20110217
LR  - 20181201
IS  - 1873-2496 (Electronic)
IS  - 1078-1439 (Linking)
VI  - 28
IP  - 6
DP  - 2010 Nov-Dec
TI  - Mass screening of prostate cancer in Vietnam: current status and our opinions.
PG  - 673-6
LID - 10.1016/j.urolonc.2009.12.008 [doi]
AB  - BACKGROUND: Although prostate cancer (CaP) is the most common male cancer in 
      developed countries, the incidence of CaP in Vietnam remains unknown and the 
      patients often seek treatment at a late stage in their illness. The mass 
      screening of CaP, which has been performed since Jan 2008 in Binh Dan hospital 
      (Ho Chi Minh City) aims to evaluate the effect of CaP mass screening in Vietnam. 
      The details of CaP treatment from 1999 to now in Ho Chi Minh City (HCMC) were 
      also used for evaluation and comparison. MATERIALS AND METHODS: From the first 
      quarter of 2008, we started a free CaP screening program in HCMC. There were 408 
      cases during first round of results. When inspecting CaP treatment, all papers 
      and studies of CaP at Binh Dan hospital from 1999 were analyzed, including 1,775 
      CaPs treated. RESULTS AND DISCUSSIONS: A total of 408 subjects were screened 
      during the CaP program. Prostate biopsies were carried out on 87 men (21.3%) 
      based on PSA values and DRE results. Ten of these biopsied men (2.5%) were 
      diagnosed with CaP, mostly with Gleason's scores of 5 to 7 and in an early 
      clinical stage. In reviewing CaP treatment from 1999 to 2009, complete androgen 
      blockade/maximal androgen blockade (MAB/CAB) was widely used, while chemotherapy 
      and radiotherapy were not routinely used. Open and laparoscopic total 
      prostatectomy remarkably increased due to the many efforts of CaP screening. The 
      number of CaP cases has now reached and overtaken the number of bladder cancer 
      cases in our hospital. Similarly, early diagnosis rates have increased in 
      parallel with radical treatment. CONCLUSION: Our initial outcomes reflected a low 
      prevalence of CaP in general (2,5%), but a high occurrence of medium grade 
      lesions (Gleason 7) among patients who tested positive for CaP. On one hand, this 
      observation highlights the value of the CaP screening programs in alerting 
      doctors/people and detecting more cases in the early stages of development. On 
      the other hand, the benefit of a mass screening program for CaP is not proven. 
      Meanwhile, selective CaP screening takes advantage of diagnosis and treatment in 
      our country.
CI  - Copyright (c) 2010 Elsevier Inc. All rights reserved.
FAU - Vu Le, Chuyen
AU  - Vu Le C
AD  - Department of Urology, Binh dan Hospital, Ho Chi Minh City, Vietnam. 
      vulechuyen@hotmail.com
FAU - Dao, Oanh Quang
AU  - Dao OQ
FAU - Khac Tran, Linh Ngoc
AU  - Khac Tran LN
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Urol Oncol
JT  - Urologic oncology
JID - 9805460
SB  - IM
MH  - Early Detection of Cancer/*methods/statistics & numerical data
MH  - Humans
MH  - Male
MH  - Mass Screening/*methods/statistics & numerical data
MH  - Prevalence
MH  - Prostatic Neoplasms/*diagnosis/*epidemiology
MH  - Vietnam/epidemiology
EDAT- 2010/11/11 06:00
MHDA- 2011/02/18 06:00
CRDT- 2010/11/11 06:00
PHST- 2009/10/07 00:00 [received]
PHST- 2009/12/08 00:00 [revised]
PHST- 2009/12/09 00:00 [accepted]
PHST- 2010/11/11 06:00 [entrez]
PHST- 2010/11/11 06:00 [pubmed]
PHST- 2011/02/18 06:00 [medline]
AID - S1078-1439(09)00418-9 [pii]
AID - 10.1016/j.urolonc.2009.12.008 [doi]
PST - ppublish
SO  - Urol Oncol. 2010 Nov-Dec;28(6):673-6. doi: 10.1016/j.urolonc.2009.12.008.