PMID- 21072552
OWN - NLM
STAT- MEDLINE
DCOM- 20110927
LR  - 20220408
IS  - 1434-9949 (Electronic)
IS  - 0770-3198 (Linking)
VI  - 30
IP  - 5
DP  - 2011 May
TI  - Health-related quality of life in Moroccan patients with ankylosing spondylitis.
PG  - 673-7
LID - 10.1007/s10067-010-1613-1 [doi]
AB  - The main objective of this study was to assess the aspects of health-related 
      quality of life (QOL) in patients with ankylosing spondylitis (AS) and to explore 
      the disease-related parameters influencing it. One hundred patients with AS 
      according to New York Classification criteria were recruited in this 
      cross-sectional study. The Medical Outcomes Study Short Form 36 Health Survey 
      (SF-36) was used to assess health-related QOL. Assessment criteria included the 
      evaluation of disease activity (Bath Ankylosing Spondylitis Disease Activity 
      index [BASDAI]), global well-being (Bath Ankylosing Spondylitis Global Index 
      [BASGI]), enthesitis (Mander enthesis index [MEI]), functional status (Bath 
      Ankylosing Spondylitis Functional Index [BASFI]); metrology (Bath Ankylosing 
      Spondylitis Metrology Index [BASMI]) and radiographic damage (Bath Ankylosing 
      Spondylitis Radiologic Index [BASRI]). In this study, males comprised 67% of the 
      subjects; mean age was 38 +/- 13 years and mean disease duration was 9.5 +/- 6.8 
      years. Among these patients, 52% had hip involvement. Our patients had a 
      moderately active disease and severe functional disability. All domains of SF-36 
      were deteriorated with low scores. The SF-36 subgroups most affected were role 
      limitation (18.8 +/- 28.1), role emotional (19.4 +/- 35), general health (44.9 +/- 
      20.3) and vitality (38.0 +/- 18.2). Lower scores of SF-36 had good statistically 
      significant correlations with altered functional status (BASFI), worse general 
      well-being (BASGI), altered metrology (BASMI); and moderate correlations with 
      high disease activity (BASDAI), important radiological damage (BASRI); restricted 
      chest expansion and prolonged morning stiffness (p < 0.001). This study states 
      that health-related QOL in Moroccan patients with AS is damaged in a significant 
      way. Mental as well as physical aspects were affected. Functional disability, 
      patient's well-being, metrology and disease activity are the main factors 
      associated with deteriorating domains of QOL in AS. Recognizing complicated 
      relationships between clinical measures and QOL in patients with AS can help us 
      to develop further management strategies to improve their QOL.
FAU - Ibn Yacoub, Yousra
AU  - Ibn Yacoub Y
AD  - Department of Rheumatology, El Ayachi Hospital, University Hospital of Rabat, 
      Sale, 11000, Morocco. yiy2005@hotmail.com
FAU - Amine, Bouchra
AU  - Amine B
FAU - Laatiris, Assia
AU  - Laatiris A
FAU - Abouqal, Redouane
AU  - Abouqal R
FAU - Hajjaj-Hassouni, Najia
AU  - Hajjaj-Hassouni N
LA  - eng
PT  - Journal Article
DEP - 20101031
PL  - Germany
TA  - Clin Rheumatol
JT  - Clinical rheumatology
JID - 8211469
SB  - IM
MH  - Adult
MH  - Cross-Sectional Studies
MH  - Female
MH  - Health Status
MH  - Health Surveys
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Morocco
MH  - Quality of Life
MH  - Research Design
MH  - Severity of Illness Index
MH  - Spondylitis, Ankylosing/*epidemiology/ethnology/*psychology
MH  - Surveys and Questionnaires
MH  - Treatment Outcome
EDAT- 2010/11/13 06:00
MHDA- 2011/09/29 06:00
CRDT- 2010/11/13 06:00
PHST- 2010/08/21 00:00 [received]
PHST- 2010/10/21 00:00 [accepted]
PHST- 2010/09/16 00:00 [revised]
PHST- 2010/11/13 06:00 [entrez]
PHST- 2010/11/13 06:00 [pubmed]
PHST- 2011/09/29 06:00 [medline]
AID - 10.1007/s10067-010-1613-1 [doi]
PST - ppublish
SO  - Clin Rheumatol. 2011 May;30(5):673-7. doi: 10.1007/s10067-010-1613-1. Epub 2010 
      Oct 31.