PMID- 21077957
OWN - NLM
STAT- MEDLINE
DCOM- 20120522
LR  - 20111213
IS  - 1399-0012 (Electronic)
IS  - 0902-0063 (Linking)
VI  - 25
IP  - 6
DP  - 2011 Nov-Dec
TI  - Kidney transplant performed after liver transplant: a single center experience.
PG  - 915-20
LID - 10.1111/j.1399-0012.2010.01369.x [doi]
AB  - Changes in liver allocation due to institution of the model for end-stage liver 
      disease/PELD criteria have led to an increase in the number of patients receiving 
      liver transplants who have elevated creatinine. Whether these patients' renal 
      dysfunction is reversible or not and whether they should receive combined liver 
      and kidney transplants (KTXs) are individualized decisions, although some 
      criteria are becoming clearer. A part of this decision must consider the outcomes 
      of patients who have liver transplants alone but later require KTXs. We herein 
      describe our single-center experience with this patient population. Our data show 
      that KTX subsequent to liver transplantation (TX) is generally safe and 
      effective, with a possibly higher surgical complication rate than standard KTX. 
      Outcomes analysis showed not statistically different patient survival of KTXs 
      performed after liver transplant (KALT) compared with KTX alone. Death censored 
      graft survival was statistically lower in the KALT group but this largely accrued 
      in the first three yr after transplant and was nearly equivalent by 10 yr.
CI  - (c) 2010 John Wiley & Sons A/S.
FAU - Levine, Matthew H
AU  - Levine MH
AD  - Division of Transplant Surgery, Department of Surgery, University of 
      Pennsylvania, Philadelphia, PA 19104, USA. matthew.h.levine@uphs.upenn.edu
FAU - Parekh, Justin
AU  - Parekh J
FAU - Feng, Sandy
AU  - Feng S
FAU - Freise, Chris
AU  - Freise C
LA  - eng
GR  - 234-2005-370011C/PHS HHS/United States
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
DEP - 20101116
PL  - Denmark
TA  - Clin Transplant
JT  - Clinical transplantation
JID - 8710240
SB  - IM
MH  - Adult
MH  - Child
MH  - End Stage Liver Disease/*therapy
MH  - Female
MH  - Follow-Up Studies
MH  - Graft Rejection/*prevention & control
MH  - Humans
MH  - Kidney Diseases/*therapy
MH  - Kidney Transplantation/*mortality
MH  - Liver Transplantation/*mortality
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Survival Rate
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2010/11/17 06:00
MHDA- 2012/05/23 06:00
CRDT- 2010/11/17 06:00
PHST- 2010/11/17 06:00 [entrez]
PHST- 2010/11/17 06:00 [pubmed]
PHST- 2012/05/23 06:00 [medline]
AID - 10.1111/j.1399-0012.2010.01369.x [doi]
PST - ppublish
SO  - Clin Transplant. 2011 Nov-Dec;25(6):915-20. doi: 
      10.1111/j.1399-0012.2010.01369.x. Epub 2010 Nov 16.