PMID- 21087243
OWN - NLM
STAT- MEDLINE
DCOM- 20110509
LR  - 20140730
IS  - 1528-1167 (Electronic)
IS  - 0013-9580 (Linking)
VI  - 52
IP  - 3
DP  - 2011 Mar
TI  - Video-EEG monitoring: safety and adverse events in 507 consecutive patients.
PG  - 443-52
LID - 10.1111/j.1528-1167.2010.02782.x [doi]
AB  - PURPOSE: Video-electroencephalography (EEG) monitoring plays a central role in 
      the presurgical evaluation of medically refractory epilepsies and the diagnosis 
      of nonepileptic attack disorders (NEADs). The aim of this study was to analyze 
      safety and adverse events (AEs) during video-EEG monitoring. METHODS: We 
      retrospectively evaluated 596 video-EEG sessions in 507 patients (233 men, mean 
      age 36 years, standard deviation = 14, range 9-80 years) within a 6-year period. 
      AEs were examined in detail and their risk factors were assessed using multiple 
      logistic regression analysis. KEY FINDINGS: Forty-four patients (9%) experienced 
      53 AEs: 20 had psychiatric events (17 postictal psychosis, 2 panic attacks, 1 
      interictal psychosis), 15 had injuries (14 falls with minor injuries, 2 falls 
      with fractures, 2 fractures without fall, 1 fall with epidural hematoma), 10 
      patients had 13 episodes of status epilepticus (SE), and one AE was 
      treatment-related (valproic acid--induced encephalopathy). Patients with AEs were 
      older (p = 0.036) and had a longer duration of epilepsy (p = 0.019). All AEs 
      resulted in a prolonged hospital stay (p < 0.001). Ninety-one percent of the AEs 
      occurred within the first 4 days of monitoring. Independent risk factors were 
      duration of epilepsy >17 years [odds ratio (OR) 3.096; 95% confidence interval 
      (CI) 1.548-6.189], a previous history of psychiatric illness (OR 16.882; 95% CI 
      5.469-52.110), a history of seizure-related injuries (OR 3.542; 95% CI 
      1.069-11.739), or a history of SE (OR 3.334; 95% CI 1.297-8.565). SIGNIFICANCE:   
      The most common AEs were postictal psychosis, falls, and SE. Patients with an 
      older age, long disease duration, psychiatric comorbidity, history of injuries, 
      and SE have a higher risk.
CI  - Wiley Periodicals, Inc. (c) 2010 International League Against Epilepsy.
FAU - Dobesberger, Judith
AU  - Dobesberger J
AD  - Department of Neurology, Innsbruck Medical University, Innsbruck, Austria.
FAU - Walser, Gerald
AU  - Walser G
FAU - Unterberger, Iris
AU  - Unterberger I
FAU - Seppi, Klaus
AU  - Seppi K
FAU - Kuchukhidze, Giorgi
AU  - Kuchukhidze G
FAU - Larch, Julia
AU  - Larch J
FAU - Bauer, Gerhard
AU  - Bauer G
FAU - Bodner, Thomas
AU  - Bodner T
FAU - Falkenstetter, Tina
AU  - Falkenstetter T
FAU - Ortler, Martin
AU  - Ortler M
FAU - Luef, Gerhard
AU  - Luef G
FAU - Trinka, Eugen
AU  - Trinka E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20101118
PL  - United States
TA  - Epilepsia
JT  - Epilepsia
JID - 2983306R
RN  - 0 (Anticonvulsants)
SB  - IM
MH  - Adult
MH  - Anticonvulsants/administration & dosage/adverse effects
MH  - Electrodes, Implanted/adverse effects
MH  - Electroencephalography/*adverse effects
MH  - Epilepsy/*diagnosis/drug therapy/etiology/surgery
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Monitoring, Physiologic/*adverse effects
MH  - Risk Factors
MH  - Safety Management
MH  - *Signal Processing, Computer-Assisted
MH  - Substance Withdrawal Syndrome/diagnosis
MH  - Vagus Nerve Stimulation/adverse effects
MH  - *Video Recording
EDAT- 2010/11/23 06:00
MHDA- 2011/05/10 06:00
CRDT- 2010/11/20 06:00
PHST- 2010/11/20 06:00 [entrez]
PHST- 2010/11/23 06:00 [pubmed]
PHST- 2011/05/10 06:00 [medline]
AID - 10.1111/j.1528-1167.2010.02782.x [doi]
PST - ppublish
SO  - Epilepsia. 2011 Mar;52(3):443-52. doi: 10.1111/j.1528-1167.2010.02782.x. Epub 
      2010 Nov 18.