PMID- 21091320
OWN - NLM
STAT- MEDLINE
DCOM- 20110906
LR  - 20110526
IS  - 1931-8405 (Electronic)
IS  - 0889-2229 (Linking)
VI  - 27
IP  - 6
DP  - 2011 Jun
TI  - Short communication: persistence of high blood levels of the chemokines CCL2, 
      CCL19, and CCL20 during the course of HIV infection.
PG  - 655-7
AB  - Dendritic cells (DCs) are important mediators of the immune response against HIV 
      and yet blood DC numbers fall substantially during HIV infection. Here we report 
      that blood levels of the DC-tissue tropic chemokines monocyte chemotactic protein 
      (MCP-1/CCL2), macrophage inflammatory proteins (MIP-3alpha/CCL20), and MIP-3beta/CCL19 
      remained elevated throughout the course of HIV infection suggesting that the 
      relatively low levels of blood circulating DCs may be due to active recruitment 
      of these cells to peripheral sites to fight disease progression.
FAU - Fontaine, Julie
AU  - Fontaine J
AD  - Laboratoire d'Immunogenetique, Centre de Recherche du Centre Hospitalier de 
      l'Universite de Montreal, Montreal, Canada.
FAU - Poudrier, Johanne
AU  - Poudrier J
FAU - Roger, Michel
AU  - Roger M
LA  - eng
GR  - Canadian Institutes of Health Research/Canada
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110123
PL  - United States
TA  - AIDS Res Hum Retroviruses
JT  - AIDS research and human retroviruses
JID - 8709376
RN  - 0 (CCL19 protein, human)
RN  - 0 (CCL2 protein, human)
RN  - 0 (CCL20 protein, human)
RN  - 0 (Chemokine CCL19)
RN  - 0 (Chemokine CCL2)
RN  - 0 (Chemokine CCL20)
SB  - IM
MH  - Blood Chemical Analysis
MH  - Chemokine CCL19/*blood
MH  - Chemokine CCL2/*blood
MH  - Chemokine CCL20/*blood
MH  - Dendritic Cells/*immunology
MH  - HIV Infections/*immunology/*physiopathology
MH  - Humans
EDAT- 2010/11/26 06:00
MHDA- 2011/09/07 06:00
CRDT- 2010/11/25 06:00
PHST- 2010/11/25 06:00 [entrez]
PHST- 2010/11/26 06:00 [pubmed]
PHST- 2011/09/07 06:00 [medline]
AID - 10.1089/aid.2010.0261 [doi]
PST - ppublish
SO  - AIDS Res Hum Retroviruses. 2011 Jun;27(6):655-7. doi: 10.1089/aid.2010.0261. Epub 
      2011 Jan 23.