PMID- 2109453 OWN - NLM STAT- MEDLINE DCOM- 19900521 LR - 20180216 IS - 0001-5792 (Print) IS - 0001-5792 (Linking) VI - 83 IP - 3 DP - 1990 TI - Iron overload in untransfused patients with hemoglobin H disease. PG - 137-9 AB - Two Chinese patients with hemoglobin (Hb) H disease without a history of blood transfusion developed iron overload at the age of 45 and 53 years, respectively. Human leukocyte antigen (HLA) system types of these 2 patients were A19, A11, B13, B62 and A2, A24, BW55, respectively, which are not related to the common haplotypes for idiopathic hemochromatosis. Since severe iron loading is a rare clinical manifestation in untransfused patients with Hb H disease, the iron overload in both patients may be due to environmental or underlying genetic factors. FAU - Lin, C K AU - Lin CK AD - Division of Hematology, Veterans General Hospital, Taipei, Taiwan, Republic of China. FAU - Peng, H W AU - Peng HW FAU - Ho, C H AU - Ho CH FAU - Yung, C H AU - Yung CH LA - eng PT - Case Reports PT - Journal Article PL - Switzerland TA - Acta Haematol JT - Acta haematologica JID - 0141053 RN - E1UOL152H7 (Iron) SB - IM MH - Humans MH - Iron/*metabolism MH - Male MH - Middle Aged MH - Thalassemia/genetics/*metabolism EDAT- 1990/01/01 00:00 MHDA- 1990/01/01 00:01 CRDT- 1990/01/01 00:00 PHST- 1990/01/01 00:00 [pubmed] PHST- 1990/01/01 00:01 [medline] PHST- 1990/01/01 00:00 [entrez] AID - 10.1159/000205190 [doi] PST - ppublish SO - Acta Haematol. 1990;83(3):137-9. doi: 10.1159/000205190.