PMID- 21096904
OWN - NLM
STAT- MEDLINE
DCOM- 20110329
LR  - 20200928
IS  - 2375-7477 (Print)
IS  - 2375-7477 (Linking)
VI  - 2010
DP  - 2010
TI  - Assessment of nonlinear interactions in event-related potentials (ERPs) elicited 
      by stimuli presented at short inter-stimulus intervals.
PG  - 4834-7
LID - 10.1109/IEMBS.2010.5627441 [doi]
AB  - The recording of brain event-related potentials (ERPs) is a widely used technique 
      to investigate the neural basis of sensory perception and cognitive processing in 
      humans.. However, when the temporal interval between two consecutive stimuli used 
      to elicit ERPs is smaller than the latency of the main ERP peaks, i.e., when the 
      stimuli are presented at a fast rate, overlaps between the ERPs elicited by 
      successive stimuli may occur. These overlaps are usually dealt with by assuming 
      that there is no nonlinear interaction between these responses, and thereby by 
      performing algebraic waveform subtractions. Here we propose a straightforward 
      approach to assess the presence of nonlinear interactions in a ERPs. This 
      approach is a direct consequence of the concept of nonlinearity between two 
      successive impulsive-like stimuli. By applying this approach to ERPs elicited by 
      nociceptive cutaneous stimuli delivered at inter-stimulus intervals (ISIs) 
      ranging from 250 ms to 2000 ms, we provide evidence that there are no nonlinear 
      interactions between nociceptive ERPs, even at the shortest ISIs.
FAU - Mitsis, Georgios D
AU  - Mitsis GD
AD  - Department of Electrical and Computer Engineering, University of Cyprus, Nicosia 
      1678, Cyprus. gmitsis@ucy.ac.cy
FAU - Iannetti, Gian Domenico
AU  - Iannetti GD
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Annu Int Conf IEEE Eng Med Biol Soc
JT  - Annual International Conference of the IEEE Engineering in Medicine and Biology 
      Society. IEEE Engineering in Medicine and Biology Society. Annual International 
      Conference
JID - 101763872
SB  - IM
MH  - Adult
MH  - Computer Simulation
MH  - Electroencephalography/*methods
MH  - Evoked Potentials, Somatosensory/*physiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Models, Neurological
MH  - Nonlinear Dynamics
MH  - Physical Stimulation/*methods
MH  - Somatosensory Cortex/*physiology
EDAT- 2010/11/26 06:00
MHDA- 2011/03/30 06:00
CRDT- 2010/11/25 06:00
PHST- 2010/11/25 06:00 [entrez]
PHST- 2010/11/26 06:00 [pubmed]
PHST- 2011/03/30 06:00 [medline]
AID - 10.1109/IEMBS.2010.5627441 [doi]
PST - ppublish
SO  - Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:4834-7. doi: 
      10.1109/IEMBS.2010.5627441.