PMID- 21097487
OWN - NLM
STAT- MEDLINE
DCOM- 20110118
LR  - 20180126
IS  - 1471-6771 (Electronic)
IS  - 0007-0912 (Linking)
VI  - 106
IP  - 1
DP  - 2011 Jan
TI  - Comparison between pulse waveform analysis and thermodilution cardiac output 
      determination in patients with severe pre-eclampsia.
PG  - 77-81
LID - 10.1093/bja/aeq292 [doi]
AB  - BACKGROUND: This study compared cardiac output (CO) measurements derived from 
      pulse waveform analysis with values obtained by thermodilution (TD), in patients 
      with post-partum complications of severe pre-eclampsia. METHODS: Eighteen 
      patients were recruited, 24-96 h post-delivery. After central venous calibration 
      of the pulse waveform analysis monitor (LiDCOplus), CO readings were compared 
      with those obtained by the TD method and repeated twice at 15 min intervals. The 
      comparison was repeated after peripheral venous calibration. Further comparisons 
      were made in eight patients at 120 and 240 min after peripheral venous 
      calibration. RESULTS: Data were pooled for measurements at 0, 15, and 30 min 
      after calibration. For the comparison between TD and LiDCOplus using central 
      venous calibration, TD exhibited a significant positive bias of 0.58 litre min(-)(1) 
      [95% confidence interval (CI): 0.77 to 0.39]. After peripheral venous 
      calibration, there was no significant bias [0.16 litre min(-)(1) (95% CI: -0.37 to 
      0.06)]. The estimated limits of agreement for central and peripheral venous 
      calibrations were -2.12 to 0.96 and -1.50 to 1.20 litre min(-)(1), respectively. When 
      comparing LiDCOplus and TD, there was no time-based effect at 120 or 240 min 
      post-peripheral calibration. CONCLUSIONS: Central and peripheral venous 
      calibrations of the LiDCOplus monitor were associated with clinically 
      insignificant bias when compared with TD. Limits of agreement were within the 
      recommendation of 30% for acceptance of a new CO technique when compared with 
      current reference methods. This form of minimally invasive CO monitoring may have 
      a valuable role in obstetric critical care.
FAU - Dyer, R A
AU  - Dyer RA
AD  - D23 Department of Anaesthesia, University of Cape Town and Groote Schuur 
      Hospital, Observatory, 7925 Cape Town, South Africa. robert.dyer@uct.ac.za
FAU - Piercy, J L
AU  - Piercy JL
FAU - Reed, A R
AU  - Reed AR
FAU - Strathie, G W
AU  - Strathie GW
FAU - Lombard, C J
AU  - Lombard CJ
FAU - Anthony, J A
AU  - Anthony JA
FAU - James, M F
AU  - James MF
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20101118
PL  - England
TA  - Br J Anaesth
JT  - British journal of anaesthesia
JID - 0372541
SB  - IM
MH  - Calibration
MH  - *Cardiac Output
MH  - Female
MH  - Humans
MH  - Monitoring, Physiologic/methods
MH  - Pre-Eclampsia/*physiopathology
MH  - Pregnancy
MH  - Prospective Studies
MH  - Puerperal Disorders/etiology/*physiopathology/therapy
MH  - Signal Processing, Computer-Assisted
MH  - Thermodilution/methods
EDAT- 2010/11/26 06:00
MHDA- 2011/01/19 06:00
CRDT- 2010/11/25 06:00
PHST- 2010/11/25 06:00 [entrez]
PHST- 2010/11/26 06:00 [pubmed]
PHST- 2011/01/19 06:00 [medline]
AID - S0007-0912(17)33365-2 [pii]
AID - 10.1093/bja/aeq292 [doi]
PST - ppublish
SO  - Br J Anaesth. 2011 Jan;106(1):77-81. doi: 10.1093/bja/aeq292. Epub 2010 Nov 18.