PMID- 21099104
OWN - NLM
STAT- MEDLINE
DCOM- 20110114
LR  - 20211020
IS  - 1558-8238 (Electronic)
IS  - 0021-9738 (Print)
IS  - 0021-9738 (Linking)
VI  - 120
IP  - 12
DP  - 2010 Dec
TI  - Which species are in your feces?
PG  - 4182-5
LID - 45263 [pii]
LID - 10.1172/JCI45263 [doi]
AB  - Nosocomial infections (i.e., infections acquired as a result of treatment in a 
      hospital or health care unit) result in approximately 100,000 deaths and cost 
      more than 25 billion dollars per year in the US alone. These infections are 
      caused primarily by bacteria and affect mainly immunosuppressed patients. 
      However, not all patients acquire infections, and the events leading up to 
      infection are unclear. In this issue of the JCI, Ubeda et al. report how 
      acquisition of one such infection, vancomycin-resistant Enterococcus faecium 
      (VRE), is linked to a shift in the microbial flora following antibiotic 
      treatment. This study highlights the potential for high-throughput sequencing of 
      intestinal microbiota as a means to identify high-risk populations.
FAU - Zaph, Colby
AU  - Zaph C
AD  - Biomedical Research Centre, Department of Pathology and Laboratory Medicine, 
      University of British Columbia, Vancouver, British Columbia, Canada. 
      colby@brc.ubc.ca
LA  - eng
GR  -  MOP-106623/Canadian Institutes of Health Research/Canada
GR  -  MOP-89773/Canadian Institutes of Health Research/Canada
PT  - Comment
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20101122
PL  - United States
TA  - J Clin Invest
JT  - The Journal of clinical investigation
JID - 7802877
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
CON - J Clin Invest. 2010 Dec;120(12):4332-41. PMID: 21099116
MH  - Anti-Bacterial Agents/adverse effects
MH  - Cross Infection/etiology/*microbiology
MH  - Enterococcus faecium/drug effects/isolation & purification
MH  - Feces/*microbiology
MH  - Gram-Positive Bacterial Infections/etiology/microbiology
MH  - Humans
MH  - Metagenome/drug effects
MH  - Vancomycin Resistance
PMC - PMC2993606
EDAT- 2010/11/26 06:00
MHDA- 2011/01/15 06:00
PMCR- 2010/12/31
CRDT- 2010/11/25 06:00
PHST- 2010/11/25 06:00 [entrez]
PHST- 2010/11/26 06:00 [pubmed]
PHST- 2011/01/15 06:00 [medline]
PHST- 2010/12/31 00:00 [pmc-release]
AID - 45263 [pii]
AID - 10.1172/JCI45263 [doi]
PST - ppublish
SO  - J Clin Invest. 2010 Dec;120(12):4182-5. doi: 10.1172/JCI45263. Epub 2010 Nov 22.