PMID- 21112438
OWN - NLM
STAT- MEDLINE
DCOM- 20110111
LR  - 20211020
IS  - 1532-821X (Electronic)
IS  - 0003-9993 (Print)
IS  - 0003-9993 (Linking)
VI  - 91
IP  - 12
DP  - 2010 Dec
TI  - Accelerometry and its association with objective markers of walking limitations 
      in ambulatory adults with multiple sclerosis.
PG  - 1942-7
LID - 10.1016/j.apmr.2010.08.011 [doi]
AB  - OBJECTIVE: To validate accelerometry based on its correlations with 6-minute walk 
      distance (6MWD) and oxygen cost of walking as objective markers of walking 
      limitations in multiple sclerosis (MS). DESIGN: Cross-sectional. SETTING: 
      Laboratory and general community. PARTICIPANTS: Ambulatory participants with MS 
      (N=26) who resided in the local community. INTERVENTIONS: Not applicable. MAIN 
      OUTCOME MEASURES: Patient Determined Disease Steps (PDDS) scale and Multiple 
      Sclerosis Walking Scale-12 (MSWS-12); 6-minute walk test while wearing a portable 
      metabolic unit for measuring the 6MWD and oxygen cost of walking; accelerometer 
      during the waking hours of a 7-day period. RESULTS: The average of total daily 
      movement counts from the accelerometer correlated significantly and strongly with 
      MSWS-12 scores (rho=-.681, P=.001), PDDS scores (rho=-.609, P=.001), 6MWD (rho=.519, 
      P=.003), and oxygen cost of walking (rho=-.541, P=.002). CONCLUSIONS: We provide 
      evidence that further supports the validity of accelerometry as a measure of 
      walking limitations in ambulatory persons with MS.
CI  - Copyright (c) 2010 American Congress of Rehabilitation Medicine. Published by 
      Elsevier Inc. All rights reserved.
FAU - Motl, Robert W
AU  - Motl RW
AD  - Department of Kinesiology and Community Health, University of Illinois at 
      Urbana-Champaign, 61801, USA. robmotl@uiuc.edu
FAU - Dlugonski, Deirdre
AU  - Dlugonski D
FAU - Suh, Yoojin
AU  - Suh Y
FAU - Weikert, Madeline
AU  - Weikert M
FAU - Fernhall, Bo
AU  - Fernhall B
FAU - Goldman, Myla
AU  - Goldman M
LA  - eng
GR  - K23 NS062898/NS/NINDS NIH HHS/United States
GR  - K23 NS062898-03/NS/NINDS NIH HHS/United States
PT  - Journal Article
PL  - United States
TA  - Arch Phys Med Rehabil
JT  - Archives of physical medicine and rehabilitation
JID - 2985158R
SB  - IM
MH  - Acceleration
MH  - Adult
MH  - Cross-Sectional Studies
MH  - Female
MH  - Gait Disorders, Neurologic/*physiopathology
MH  - Humans
MH  - Male
MH  - Multiple Sclerosis/*physiopathology
MH  - Oxygen Consumption/physiology
MH  - Walking/*physiology
PMC - PMC3165019
MID - NIHMS309677
EDAT- 2010/11/30 06:00
MHDA- 2011/01/12 06:00
PMCR- 2011/09/02
CRDT- 2010/11/30 06:00
PHST- 2010/06/25 00:00 [received]
PHST- 2010/08/03 00:00 [accepted]
PHST- 2010/11/30 06:00 [entrez]
PHST- 2010/11/30 06:00 [pubmed]
PHST- 2011/01/12 06:00 [medline]
PHST- 2011/09/02 00:00 [pmc-release]
AID - S0003-9993(10)00715-X [pii]
AID - 10.1016/j.apmr.2010.08.011 [doi]
PST - ppublish
SO  - Arch Phys Med Rehabil. 2010 Dec;91(12):1942-7. doi: 10.1016/j.apmr.2010.08.011.