PMID- 21114210
OWN - NLM
STAT- MEDLINE
DCOM- 20101221
LR  - 20191210
IS  - 0125-2208 (Print)
IS  - 0125-2208 (Linking)
VI  - 93
IP  - 11
DP  - 2010 Nov
TI  - Application of the multiple drugs immunoassay test for rapid detection of drug 
      abuse in postmortem urine.
PG  - 1301-9
AB  - OBJECTIVE: The ADVANCED QUALITY One Step Multi-Drug Screen test is a new urine 
      on-site immunoassay test that is designed to detect multiple drugs of abuse in 
      one time (barbiturates, benzodiazepines, cocaine, methylenedioxymethamphetamine 
      (MDMA), methamphetamine, and opiates group). Thus, the present research was done 
      to evaluate the diagnostic performance of this test. MATERIAL AND METHOD: Urine 
      samples obtained from corpses subjected to medicolegal autopsy at the forensic 
      unit in Ramathibodi Hospital between October 2007 and March 2009 were used for 
      the present study. The diagnostic performance of this immunoassay test was 
      determined by using the results of the rapid emergency drug identification high 
      sensitivity (REMEDi HS) system as the gold standard. RESULTS: Two hundred forty 
      six urine samples were used in the present study. The sensitivity with their 95% 
      confidence interval of cocaine, opiates, methamphetamine, and benzodiazepines 
      assay was 100% (100-100%) each. The specificity with their 95% confidence 
      interval of these was 100% (100-100%), 98% (96.75-99.94%), 95% (91.70-97.38%), 
      and 93% (89.89-96.24%), respectively. The MDMA and barbiturates were not 
      evaluated because there was no true positive result. CONCLUSION: The ADVANCED 
      QUALITY One Step Multi-Drug Screen test is reliable for drugs of abuse screening 
      in postmortem urine.
FAU - Srisont, Smith
AU  - Srisont S
AD  - Department ofPathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol 
      University, Bangkok, Thailand. smithfa118@yahoo.com
FAU - Chirachariyavej, Thamrong
AU  - Chirachariyavej T
FAU - Peonim, A V M Vichan
AU  - Peonim AV
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - Thailand
TA  - J Med Assoc Thai
JT  - Journal of the Medical Association of Thailand = Chotmaihet thangphaet
JID - 7507216
RN  - 0 (Illicit Drugs)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Autopsy
MH  - Cadaver
MH  - Female
MH  - *Forensic Medicine
MH  - Humans
MH  - Illicit Drugs/*urine
MH  - Immunoassay/*methods
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Substance Abuse Detection/*methods
MH  - Substance-Related Disorders/*urine
MH  - Young Adult
EDAT- 2010/12/01 06:00
MHDA- 2010/12/22 06:00
CRDT- 2010/12/01 06:00
PHST- 2010/12/01 06:00 [entrez]
PHST- 2010/12/01 06:00 [pubmed]
PHST- 2010/12/22 06:00 [medline]
PST - ppublish
SO  - J Med Assoc Thai. 2010 Nov;93(11):1301-9.