PMID- 21125203 OWN - NLM STAT- MEDLINE DCOM- 20110214 LR - 20240317 IS - 1760-4788 (Electronic) IS - 1279-7707 (Linking) VI - 14 IP - 10 DP - 2010 Dec TI - Antioxidant activity of the new black vinegar "IZUMI". PG - 845-9 AB - OBJECTIVES: "IZUMI" is a new kind of vinegar resulting from an improvement in the manufacturing method of Kurosu, a traditional vinegar product made from unpolished rice. We evaluated the antioxidant activity of this new Kurosu by means of measuring the level of diacron-reactive oxygen metabolites (d-ROM), the biological antioxidant potential (BAP), as well as RBC deformability using the microchannel array flow method. PARTICIPANTS: Ten healthy, untrained female volunteers participated in this study. MEASUREMENTS: All subjects drank 50 ml of "IZUMI" on a daily basis, and blood samples were collected pre-"IZUMI" (I), after one month "IZUMI" consumption (II), and after two months "IZUMI" consumption (III). The subjects continuously wore a lifecorder during a 7-day period and the nutritional intake was measured before the initial blood sample collection. RESULTS: There were no significant changes in weight, BMI, fat mass, or fat-free mass. There were no significant differences in daily energy consumption, physical activity and nutritional intake. Peripheral blood variables did not change significantly. The drinking of " IZUMI " increased serum BAP level gradually, and after 30 days it was significantly higher as compared to the pre-drinking level. The serum level of d-ROM and blood filtration time (BFT) decreased by drinking "IZUMI"; with d-ROM significantly lower than the pre-drinking level after 30 days and BFT significantly decreased after 60 days (all P < 0.05). CONCLUSIONS: These results suggest that "IZUMI", a Kurosu containing a higher level of amino acids, increases antioxidant activity and reduces oxidative stress and blood filtration time in female subjects. FAU - Nagashima, M AU - Nagashima M AD - Department of Sport Life Style Management, National Institute of Fitness and Sports in Kanoya, Kanoya City, Japan. nagasima@nifs-k.ac.jp FAU - Saito, K AU - Saito K LA - eng PT - Clinical Trial PT - Journal Article PL - France TA - J Nutr Health Aging JT - The journal of nutrition, health & aging JID - 100893366 RN - 0 (Amino Acids) RN - 0 (Antioxidants) RN - 0 (Reactive Oxygen Species) RN - Q40Q9N063P (Acetic Acid) SB - IM MH - Acetic Acid/*administration & dosage/adverse effects MH - Amino Acids/administration & dosage/adverse effects/analysis MH - Antioxidants/*administration & dosage/adverse effects/*metabolism MH - *Beverages/adverse effects/analysis MH - Diet MH - Diet Records MH - Erythrocyte Deformability MH - Female MH - Fermentation MH - *Functional Food/adverse effects/analysis MH - Humans MH - Middle Aged MH - Oryza/chemistry/metabolism MH - *Oxidative Stress MH - Reactive Oxygen Species/*blood MH - Seeds/chemistry/metabolism MH - Time Factors EDAT- 2010/12/03 06:00 MHDA- 2011/02/15 06:00 CRDT- 2010/12/03 06:00 PHST- 2010/12/03 06:00 [entrez] PHST- 2010/12/03 06:00 [pubmed] PHST- 2011/02/15 06:00 [medline] AID - S1279-7707(23)02435-1 [pii] AID - 10.1007/s12603-010-0138-2 [doi] PST - ppublish SO - J Nutr Health Aging. 2010 Dec;14(10):845-9. doi: 10.1007/s12603-010-0138-2.