PMID- 21125426 OWN - NLM STAT- MEDLINE DCOM- 20120404 LR - 20211020 IS - 1522-1709 (Electronic) IS - 1520-9512 (Linking) VI - 15 IP - 4 DP - 2011 Dec TI - Long-term assessment of nocturnal Cheyne-Stokes respiration in patients with heart failure. PG - 855-60 LID - 10.1007/s11325-010-0450-4 [doi] AB - PURPOSE: Cheyne-Stokes respiration (CSR) is a known controversial prognostic marker in patients with heart failure (HF). Little is known, moreover, about the development and progress of CSR in such patients. The CSR progress over time may be indicative for clinical deterioration in patients with HF disease METHODS: Prospective cohort sleep studies, with algorithm-based analyses of continuously or periodically monitored changes over time using standard pulse oximeter. Home testing for 4 months of patients recruited from the cardiology department of a large community medical center in Haifa, Israel. A total of 36 patients, 31 men and five women, aged between 50 and 74 years, with symptomatic chronic HF. RESULTS: Out of the 36 patients, 15 (42%) patients were found to have CSR. The CSR cycle length was chosen as the characteristic parameter which determines the periodicity of the event and its length. Analyses of CSR cycle length and duration in the 15 patients showed changes over time in the length of the CSR event only in patient with New York Heart Association (NYHA) 4 classification. CONCLUSIONS: Nocturnal CSR in patients with HF show small variations over time in the prevalence or duration of the cycle length and could be a marker for entering stage 4 or deterioration in the NYHA class of HF patient. Moreover, it may take years for HF patients to develop CSR or to increase the length of the cycle length of existing CSR, if they develop it at all. FAU - Amir, Offer AU - Amir O AD - Heart Failure Center Division of Cardiology, Lady Davis Carmel Medical Center, Haifa, Israel. offeram@012.net.il FAU - Barak-Shinar, Deganit AU - Barak-Shinar D FAU - Wolff, Rafael AU - Wolff R FAU - Paz, Hagar AU - Paz H FAU - Dori, Guy AU - Dori G FAU - Smart, Frank W AU - Smart FW FAU - Lewis, Basil S AU - Lewis BS LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20101202 PL - Germany TA - Sleep Breath JT - Sleep & breathing = Schlaf & Atmung JID - 9804161 SB - IM MH - Aged MH - Algorithms MH - Cheyne-Stokes Respiration/classification/*diagnosis/physiopathology MH - Disease Progression MH - Female MH - Follow-Up Studies MH - Heart Failure/classification/*diagnosis/physiopathology MH - Hemodynamics/physiology MH - Humans MH - Male MH - Middle Aged MH - Polysomnography/*methods MH - Prognosis EDAT- 2010/12/03 06:00 MHDA- 2012/04/05 06:00 CRDT- 2010/12/03 06:00 PHST- 2010/10/17 00:00 [received] PHST- 2010/11/21 00:00 [accepted] PHST- 2010/11/16 00:00 [revised] PHST- 2010/12/03 06:00 [entrez] PHST- 2010/12/03 06:00 [pubmed] PHST- 2012/04/05 06:00 [medline] AID - 10.1007/s11325-010-0450-4 [doi] PST - ppublish SO - Sleep Breath. 2011 Dec;15(4):855-60. doi: 10.1007/s11325-010-0450-4. Epub 2010 Dec 2.