PMID- 21131238
OWN - NLM
STAT- MEDLINE
DCOM- 20110525
LR  - 20110117
IS  - 1525-5069 (Electronic)
IS  - 1525-5050 (Linking)
VI  - 20
IP  - 1
DP  - 2011 Jan
TI  - Recurrent aphasic status epilepticus after prolonged generalized tonic-clonic 
      seizures versus a special feature of Todd's paralysis.
PG  - 132-7
LID - 10.1016/j.yebeh.2010.11.001 [doi]
AB  - Postictal aphasia may be a feature of Todd's paralysis or the presentation of 
      aphasic nonconvulsive status epilepticus (NCSE). We describe a 74-year-old woman 
      with three episodes of aphasic status epilepticus after prolonged generalized 
      tonic-clonic seizures. In the first episode, the NCSE was not definitively 
      diagnosed, but an increase in the epileptic medication led to resolution of the 
      epileptic activity within 2 weeks. During the second episode, NCSE was terminated 
      within 7 days under intensified antiepileptic treatment. In the third episode, 
      phenytoin treatment led to intoxication and resulted in further treatment on an 
      intensive care unit. The patient required several months to recover from this 
      episode. NCSE in the elderly is difficult to recognize, especially when it 
      presents as a prolonged postictal deficit like aphasia. Once diagnosed it has to 
      be treated carefully, because in the elderly, aggressive treatment strategies may 
      be associated with a high risk of adverse events.
CI  - Copyright A(c) 2010 Elsevier Inc. All rights reserved.
FAU - Rosche, J
AU  - Rosche J
AD  - Klinik und Poliklinik fur Neurologie, Universitat Rostock, Rostock, Germany. 
      Johannes.roesche@med.uni-rostock.de
FAU - Schley, A
AU  - Schley A
FAU - Schwesinger, A
AU  - Schwesinger A
FAU - Grossmann, A
AU  - Grossmann A
FAU - Mach, H
AU  - Mach H
FAU - Benecke, R
AU  - Benecke R
FAU - Walter, U
AU  - Walter U
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20101204
PL  - United States
TA  - Epilepsy Behav
JT  - Epilepsy & behavior : E&B
JID - 100892858
RN  - 0 (Anticonvulsants)
SB  - IM
MH  - Aged
MH  - Anticonvulsants/therapeutic use
MH  - Aphasia/*diagnosis/drug therapy
MH  - Diagnosis, Differential
MH  - Electroencephalography
MH  - Female
MH  - Humans
MH  - Paralysis/*diagnosis
MH  - Seizures/*diagnosis/drug therapy
MH  - Status Epilepticus/*diagnosis/drug therapy
MH  - Treatment Outcome
EDAT- 2010/12/07 06:00
MHDA- 2011/05/26 06:00
CRDT- 2010/12/07 06:00
PHST- 2010/10/05 00:00 [received]
PHST- 2010/10/30 00:00 [revised]
PHST- 2010/11/01 00:00 [accepted]
PHST- 2010/12/07 06:00 [entrez]
PHST- 2010/12/07 06:00 [pubmed]
PHST- 2011/05/26 06:00 [medline]
AID - S1525-5050(10)00701-8 [pii]
AID - 10.1016/j.yebeh.2010.11.001 [doi]
PST - ppublish
SO  - Epilepsy Behav. 2011 Jan;20(1):132-7. doi: 10.1016/j.yebeh.2010.11.001. Epub 2010 
      Dec 4.