PMID- 2113451
OWN - NLM
STAT- MEDLINE
DCOM- 19900802
LR  - 20190828
IS  - 0009-5915 (Print)
IS  - 0009-5915 (Linking)
VI  - 99
IP  - 2
DP  - 1990 Apr
TI  - On the origins of tandemly repeated genes: does histone gene copy number in 
      Drosophila reflect chromosomal location?
PG  - 118-24
AB  - Widely regarded beliefs about Drosophila histone gene copy numbers and 
      developmental requirements have been generalized from fairly limited data since 
      studies on histone gene arrangements and copy numbers have been largely confined 
      to a single species, D. melanogaster. Histone gene copy numbers and chromosomal 
      locations were examined in three species: D. melangaster, D. hydei and D. 
      hawaiiensis. Quantitative whole genome blot analysis of DNA from diploid tissues 
      revealed a tenfold variability in histone gene copy numbers for these three 
      species. In situ hybridization to polytene chromosomes showed that the histone 
      DNA (hDNA) chromosomal location is different in all three species. These 
      observations lead us to propose a relationship between histone gene reiteration 
      and chromosomal position.
FAU - Fitch, D H
AU  - Fitch DH
AD  - Department of Molecular and Cell Biology, University of Connecticut, Storrs 
      06269.
FAU - Strausbaugh, L D
AU  - Strausbaugh LD
FAU - Barrett, V
AU  - Barrett V
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Austria
TA  - Chromosoma
JT  - Chromosoma
JID - 2985138R
RN  - 0 (Histones)
SB  - IM
MH  - Animals
MH  - Chromosome Banding
MH  - *Chromosome Mapping
MH  - Drosophila/*genetics
MH  - Drosophila melanogaster/*genetics
MH  - Histones/*genetics
MH  - *Multigene Family
MH  - Nucleic Acid Hybridization
EDAT- 1990/04/01 00:00
MHDA- 1990/04/01 00:01
CRDT- 1990/04/01 00:00
PHST- 1990/04/01 00:00 [pubmed]
PHST- 1990/04/01 00:01 [medline]
PHST- 1990/04/01 00:00 [entrez]
AID - 10.1007/BF01735327 [doi]
PST - ppublish
SO  - Chromosoma. 1990 Apr;99(2):118-24. doi: 10.1007/BF01735327.