PMID- 21141066
OWN - NLM
STAT- MEDLINE
DCOM- 20110203
LR  - 20131121
IS  - 1343-3490 (Print)
IS  - 1343-3490 (Linking)
VI  - 48
IP  - 11
DP  - 2010 Nov
TI  - [Case of thymic carcinoid associated with multiple endocrine neoplasia type I 
      treated effectively with chemotherapy].
PG  - 855-9
AB  - A 53-year-old man was referred to our hospital due to a mediastinal mass found 
      during a medical checkup in July 2009. He had a past history of 
      hyperparathyroidism, for which he underwent surgery in 1994, and also had a 
      family history in that his sister had multiple endocrine neoplasia type 1 (MEN1). 
      He was given a diagnosis of MEN I on genetic testing. Chest CT revealed a 
      mediastinal mass 4 cm in maximum dimension, and an atypical carcinoid was 
      diagnosed according to mediastinal biopsy findings. Bone metastasis was detected 
      and he was given cisplatin and etoposide. The tumor decreased in size by 30%, and 
      was evaluated as showing partial response. Although there are some cases of 
      MEN-related thymoma treated by surgery, a case which successfully responded to 
      chemotherapy alone is thought to be extremely rare.
FAU - Amano, Hiroyuki
AU  - Amano H
AD  - Department of Respirology, Graduate School of Medicine, Chiba University.
FAU - Yamada, Takayuki
AU  - Yamada T
FAU - Jujoh, Takayuki
AU  - Jujoh T
FAU - Kuroda, Fuminobu
AU  - Kuroda F
FAU - Sakao, Seiichiroh
AU  - Sakao S
FAU - Tada, Yuji
AU  - Tada Y
FAU - Kurosu, Katsushi
AU  - Kurosu K
FAU - Kasahara, Yasunori
AU  - Kasahara Y
FAU - Tanabe, Nobuhiro
AU  - Tanabe N
FAU - Takiguchi, Yuichi
AU  - Takiguchi Y
FAU - Tatsumi, Kouichirou
AU  - Tatsumi K
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Nihon Kokyuki Gakkai Zasshi
JT  - Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society
JID - 9808802
RN  - 6PLQ3CP4P3 (Etoposide)
RN  - Q20Q21Q62J (Cisplatin)
SB  - IM
MH  - Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
MH  - Carcinoid Tumor/*complications/diagnosis/*drug therapy
MH  - Cisplatin/administration & dosage
MH  - Etoposide/administration & dosage
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multiple Endocrine Neoplasia Type 1/*complications/diagnosis/genetics
MH  - Thymus Neoplasms/*complications/diagnosis/*drug therapy
MH  - Treatment Outcome
EDAT- 2010/12/15 06:00
MHDA- 2011/02/04 06:00
CRDT- 2010/12/15 06:00
PHST- 2010/12/15 06:00 [entrez]
PHST- 2010/12/15 06:00 [pubmed]
PHST- 2011/02/04 06:00 [medline]
PST - ppublish
SO  - Nihon Kokyuki Gakkai Zasshi. 2010 Nov;48(11):855-9.