PMID- 21144797 OWN - NLM STAT- MEDLINE DCOM- 20111221 LR - 20191210 IS - 1873-3557 (Electronic) IS - 1386-1425 (Linking) VI - 80 IP - 1 DP - 2011 Oct TI - Rapid in situ detection of street samples of drugs of abuse on textile substrates using microRaman spectroscopy. PG - 2-7 LID - 10.1016/j.saa.2010.11.001 [doi] AB - Trace amounts of street samples of cocaine hydrochloride and N-methyl-3,4-methylenedioxy-amphetamine (MDMA) on natural and synthetic textiles were successfully detected in situ using confocal Raman microscopy. The presence of some excipient bands in the spectra of the drugs did not prevent the unambiguous identification of the drugs. Raman spectra of the drugs were readily obtained without significant interference from the fibre substrates. Interfering bands arising from the fibre natural or synthetic polymer structure and/or dye molecules did not overlap with the characteristic Raman bands of the drugs. If needed, interfering bands could be successfully removed by spectral subtraction. Also, Raman spectra could be acquired from drug particles trapped between the fibres of highly fluorescent textile specimens. The total acquisition time of the spectra of the drug particles was 90 s accomplished non-destructively and without detachment from their substrates. Sample preparation was not required and spectra of the drugs could be obtained non-invasively preserving the integrity of the evidential material for further analysis. CI - Copyright (c) 2010 Elsevier B.V. All rights reserved. FAU - Ali, Esam M A AU - Ali EM AD - Division of Chemical and Forensic Sciences, University of Bradford, Bradford, UK. e.m.a.ali@bradford.ac.uk FAU - Edwards, Howell G M AU - Edwards HG FAU - Scowen, Ian J AU - Scowen IJ LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20101121 PL - England TA - Spectrochim Acta A Mol Biomol Spectrosc JT - Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy JID - 9602533 RN - 0 (Coloring Agents) RN - 0 (Illicit Drugs) RN - I5Y540LHVR (Cocaine) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM MH - Cocaine/analysis MH - Coloring Agents/chemistry MH - Forensic Sciences/methods MH - Humans MH - Illicit Drugs/*analysis MH - N-Methyl-3,4-methylenedioxyamphetamine/analysis MH - Spectrum Analysis, Raman/*methods MH - Textiles/*analysis EDAT- 2010/12/15 06:00 MHDA- 2011/12/22 06:00 CRDT- 2010/12/15 06:00 PHST- 2010/08/09 00:00 [received] PHST- 2010/11/10 00:00 [accepted] PHST- 2010/12/15 06:00 [entrez] PHST- 2010/12/15 06:00 [pubmed] PHST- 2011/12/22 06:00 [medline] AID - S1386-1425(10)00557-3 [pii] AID - 10.1016/j.saa.2010.11.001 [doi] PST - ppublish SO - Spectrochim Acta A Mol Biomol Spectrosc. 2011 Oct;80(1):2-7. doi: 10.1016/j.saa.2010.11.001. Epub 2010 Nov 21.