PMID- 21147287
OWN - NLM
STAT- MEDLINE
DCOM- 20110104
LR  - 20101214
IS  - 1097-6744 (Electronic)
IS  - 0002-8703 (Linking)
VI  - 160
IP  - 6 Suppl
DP  - 2010 Dec
TI  - Management of acute left ventricular dysfunction after primary percutaneous 
      coronary intervention for ST elevation acute myocardial infarction.
PG  - S16-21
LID - 10.1016/j.ahj.2010.10.011 [doi]
AB  - Primary percutaneous coronary intervention (PCI) decreases myocardial damage and 
      reduces the occurrence of mechanical complications and acute heart failure in 
      patients with ST elevation myocardial infarction (STEMI). Nevertheless, left 
      ventricular (LV) dysfunction remains the leading cause of in-hospital mortality 
      in all subsets of patients and particularly for those in whom primary PCI fails 
      to reopen the infarct-related artery. The clinical scenarios of acute LV failure 
      are heart failure and cardiogenic shock, both conditions being associated with 
      extremely poor outcomes. It has been estimated that LV failure accounts for >75% 
      of the cases of shock complicating acute STEMI. As compared to similar 
      situations, the decision-making process in these patients can potentially benefit 
      from the known coronary anatomy and, in many instances, from the immediate 
      implantation of an intraaortic balloon pump at the time of PCI in selected groups 
      of patients. A thorough clinical and instrumental evaluation is mandatory to 
      discriminate patients who will likely recover (either spontaneously or with 
      further conventional procedures) from those who have irreversible myocardial 
      injury and should be screened for LV assist devices and/or emergent heart 
      transplantation. In this review, we provide a practical diagnostic and 
      therapeutic algorithm that may be helpful for the clinical management of patients 
      with acute LV failure after primary PCI.
CI  - Copyright (c) 2010 Mosby, Inc. All rights reserved.
FAU - Saia, Francesco
AU  - Saia F
AD  - Institute of Cardiology, University of Bologna, Policlinico S. Orsola-Malpighi, 
      Bologna, Italy. francescosaia@hotmail.com
FAU - Grigioni, Francesco
AU  - Grigioni F
FAU - Marzocchi, Antonio
AU  - Marzocchi A
FAU - Branzi, Angelo
AU  - Branzi A
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Am Heart J
JT  - American heart journal
JID - 0370465
RN  - 0 (Cardiovascular Agents)
SB  - IM
MH  - Acute Disease
MH  - Algorithms
MH  - *Angioplasty, Balloon, Coronary
MH  - Cardiac Surgical Procedures
MH  - Cardiovascular Agents/therapeutic use
MH  - Heart Failure/*diagnosis/etiology/*therapy
MH  - Heart Transplantation
MH  - Heart-Assist Devices
MH  - Humans
MH  - Intra-Aortic Balloon Pumping
MH  - Myocardial Infarction/*complications/*therapy
MH  - Prognosis
MH  - Time Factors
MH  - Ventricular Dysfunction, Left/epidemiology/etiology/*therapy
EDAT- 2010/12/22 06:00
MHDA- 2011/01/05 06:00
CRDT- 2010/12/15 06:00
PHST- 2010/12/15 06:00 [entrez]
PHST- 2010/12/22 06:00 [pubmed]
PHST- 2011/01/05 06:00 [medline]
AID - S0002-8703(10)00911-7 [pii]
AID - 10.1016/j.ahj.2010.10.011 [doi]
PST - ppublish
SO  - Am Heart J. 2010 Dec;160(6 Suppl):S16-21. doi: 10.1016/j.ahj.2010.10.011.