PMID- 21151930
OWN - NLM
STAT- MEDLINE
DCOM- 20110705
LR  - 20211020
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 5
IP  - 12
DP  - 2010 Dec 3
TI  - Chipmunk parvovirus is distinct from members in the genus Erythrovirus of the 
      family Parvoviridae.
PG  - e15113
LID - 10.1371/journal.pone.0015113 [doi]
LID - e15113
AB  - The transcription profile of chipmunk parvovirus (ChpPV), a tentative member of 
      the genus Erythrovirus in the subfamily Parvovirinae of the family Parvoviridae, 
      was characterized by transfecting a nearly full-length genome. We found that it 
      is unique from the profiles of human parvovirus B19 and simian parvovirus, the 
      members in the genus Erythrovirus so far characterized, in that the small RNA 
      transcripts were not processed for encoding small non-structural proteins. 
      However, like the large non-structural protein NS1 of the human parvovirus B19, 
      the ChpPV NS1 is a potent inducer of apoptosis. Further phylogenetic analysis of 
      ChpPV with other parvoviruses in the subfamily Parvovirinae indicates that ChpPV 
      is distinct from the members in genus Erythrovirus. Thus, we conclude that ChpPV 
      may represent a new genus in the family Parvoviridae.
FAU - Chen, Zhaojun
AU  - Chen Z
AD  - Department of Clinical Laboratory, The Affiliated Hospital of Hangzhou Normal 
      University, Hangzhou, China.
FAU - Chen, Aaron Yun
AU  - Chen AY
FAU - Cheng, Fang
AU  - Cheng F
FAU - Qiu, Jianming
AU  - Qiu J
LA  - eng
GR  - P20 RR016443/RR/NCRR NIH HHS/United States
GR  - R01 AI070723/AI/NIAID NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20101203
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Animals
MH  - Apoptosis
MH  - COS Cells
MH  - Chlorocebus aethiops
MH  - Erythrovirus/classification/*genetics
MH  - Humans
MH  - Parvoviridae/classification/*genetics
MH  - Parvoviridae Infections/*genetics
MH  - Phylogeny
MH  - Plasmids/metabolism
MH  - Sciuridae
MH  - Transcription, Genetic
PMC - PMC2997070
COIS- Competing Interests: The authors have declared that no competing interests exist.
EDAT- 2010/12/15 06:00
MHDA- 2011/07/06 06:00
PMCR- 2010/12/03
CRDT- 2010/12/15 06:00
PHST- 2010/08/13 00:00 [received]
PHST- 2010/10/22 00:00 [accepted]
PHST- 2010/12/15 06:00 [entrez]
PHST- 2010/12/15 06:00 [pubmed]
PHST- 2011/07/06 06:00 [medline]
PHST- 2010/12/03 00:00 [pmc-release]
AID - PONE-D-10-00594 [pii]
AID - 10.1371/journal.pone.0015113 [doi]
PST - epublish
SO  - PLoS One. 2010 Dec 3;5(12):e15113. doi: 10.1371/journal.pone.0015113.