PMID- 21165234 OWN - NLM STAT- MEDLINE DCOM- 20110404 LR - 20211020 IS - 2092-9382 (Electronic) IS - 1011-8942 (Print) IS - 1011-8942 (Linking) VI - 24 IP - 6 DP - 2010 Dec TI - Characterization of peripapillary atrophy using spectral domain optical coherence tomography. PG - 353-9 LID - 10.3341/kjo.2010.24.6.353 [doi] AB - PURPOSE: To characterize the features of peripapillary atrophy (PPA), as imaged by spectral-domain optical coherence tomography (SD-OCT). METHODS: SD-OCT imaging of the optic disc was performed on healthy eyes, eyes suspected of having glaucoma, and eyes diagnosed with glaucoma. From the peripheral beta-zone, the retinal nerve fiber layer (RNFL), the junction of the inner and outer segments (IS/OS) of the photoreceptor layer, and the Bruch's membrane/retinal pigment epithelium complex layer (BRL) were visualized. RESULTS: Nineteen consecutive eyes of 10 subjects were imaged. The RNFL was observed in the PPA beta-zone of all eyes, and no eye showed an IS/OS complex in the beta-zone. The BRL was absent in the beta-zone of two eyes. The BRL was incomplete or showed posterior bowing in the beta-zone of five eyes. CONCLUSIONS: The common findings in the PPA beta-zone were that the RNFL was present, but the photoreceptor layer was absent. Presence of the BRL was variable in the beta-zone areas. FAU - Na, Jung Hwa AU - Na JH AD - Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. FAU - Moon, Byung Gil AU - Moon BG FAU - Sung, Kyung Rim AU - Sung KR FAU - Lee, Youngrok AU - Lee Y FAU - Kook, Michael S AU - Kook MS LA - eng PT - Case Reports PT - Journal Article DEP - 20101123 PL - Korea (South) TA - Korean J Ophthalmol JT - Korean journal of ophthalmology : KJO JID - 8804513 SB - IM MH - Adult MH - Aged MH - Bruch Membrane/pathology MH - Female MH - Glaucoma/*complications MH - Humans MH - Male MH - Middle Aged MH - Nerve Fibers/pathology MH - Optic Atrophy/*diagnosis/*etiology MH - Optic Disk/*pathology MH - Photoreceptor Cells, Vertebrate/pathology MH - Retina/pathology MH - Retinal Pigment Epithelium/pathology MH - Tomography, Optical Coherence/*methods PMC - PMC2992563 OTO - NOTNLM OT - Bruch's membrane OT - Glaucoma OT - Peripapillary atrophy OT - Retinal nerve fiber layer OT - Spectral-domain optical coherence tomography COIS- No potential conflict of interest relevant to this article was reported. EDAT- 2010/12/18 06:00 MHDA- 2011/04/05 06:00 PMCR- 2010/12/01 CRDT- 2010/12/18 06:00 PHST- 2010/03/15 00:00 [received] PHST- 2010/08/13 00:00 [accepted] PHST- 2010/12/18 06:00 [entrez] PHST- 2010/12/18 06:00 [pubmed] PHST- 2011/04/05 06:00 [medline] PHST- 2010/12/01 00:00 [pmc-release] AID - 10.3341/kjo.2010.24.6.353 [doi] PST - ppublish SO - Korean J Ophthalmol. 2010 Dec;24(6):353-9. doi: 10.3341/kjo.2010.24.6.353. Epub 2010 Nov 23.