PMID- 21169832 OWN - NLM STAT- MEDLINE DCOM- 20110406 LR - 20120131 IS - 1473-6527 (Electronic) IS - 0951-7375 (Linking) VI - 24 IP - 2 DP - 2011 Apr TI - Skin infections in HIV-infected individuals in the era of HAART. PG - 124-9 LID - 10.1097/QCO.0b013e328342cb31 [doi] AB - PURPOSE OF REVIEW: Clinicians should be aware of the shift in the cutaneous infectious disease burden in human immunodeficiency virus-infected individuals as a reflection of immune restoration in the era of highly active antiretroviral therapy (HAART). RECENT FINDINGS: As in the general population but to greater extent, methicillin-resistant Staphylococcus aureus (MRSA) soft-tissue infection is a rising problem among those with human immunodeficiency virus (HIV). Human papilloma virus (HPV) is exceedingly prevalent and persistent despite HAART, and HPV-associated malignancy is increasing as those with HIV live longer. Herpes, syphilis, and Kaposi's sarcoma continue to plague individuals with HIV. Immune reconstitution inflammatory syndrome (IRIS) is common and often presents with infectious cutaneous manifestations. SUMMARY: This review implicates the importance of the acknowledgment of MRSA infections risk factors, screening for HPV-related neoplasia, continuance of trials to establish the efficacy of herpes vaccines, and awareness of prevalent cutaneous infections presenting with IRIS in those with HIV. FAU - Rodgers, Sarah AU - Rodgers S AD - Department of Dermatology, Duke University Medical Center, Durham, North Carolina, USA. FAU - Leslie, Kieron S AU - Leslie KS LA - eng PT - Journal Article PT - Review PL - United States TA - Curr Opin Infect Dis JT - Current opinion in infectious diseases JID - 8809878 SB - IM MH - AIDS-Related Opportunistic Infections/chemically induced/epidemiology/*immunology MH - Antiretroviral Therapy, Highly Active/*adverse effects MH - HIV Infections/*drug therapy/immunology MH - Humans MH - Papillomavirus Infections/chemically induced/epidemiology/*immunology MH - Prevalence MH - Skin Diseases, Infectious/chemically induced/epidemiology/*immunology EDAT- 2010/12/21 06:00 MHDA- 2011/04/07 06:00 CRDT- 2010/12/21 06:00 PHST- 2010/12/21 06:00 [entrez] PHST- 2010/12/21 06:00 [pubmed] PHST- 2011/04/07 06:00 [medline] AID - 10.1097/QCO.0b013e328342cb31 [doi] PST - ppublish SO - Curr Opin Infect Dis. 2011 Apr;24(2):124-9. doi: 10.1097/QCO.0b013e328342cb31.