PMID- 21171452
OWN - NLM
STAT- MEDLINE
DCOM- 20121203
LR  - 20101220
IS  - 1000-6834 (Print)
IS  - 1000-6834 (Linking)
VI  - 17
IP  - 1
DP  - 2001 Feb
TI  - [Study on the effect of hyperbaric oxygen on apoptosis in the CA1 region of 
      hippocampus following forebrain ischemia reperfusion].
PG  - 82-4
AB  - AIM AND METHODS: To study the mechanism of hyperbaric oxygen (HBO) on the 
      treatment of cerebral ischemia, and to provide theoretical basis for hyperbaric 
      oxygen treatment (HBOT), we examined the effect of 0.15 MPa and 0.25 MPa HBO 
      treatment (60 min/d, for 3 successive days ) on ischemia reperfusion - induced 
      apoptosis in gerbil hippocampus CA1 using TUNEL staining method. RESULTS: The 
      number of neuronal apoptosis in hippocampus CA1 was significantly decreased in 
      HBOT groups(P < 0.01). Neuronal apoptosis in hippocampus CA1 in 0.25 MPa groups 
      were less than that in 0.15 MPa groups (P < 0.01). CONCLUSION: HBOT is effective 
      in reducing neuronal apoptosis and in protecting neurons from injury of ischemia 
      reperfusion, and 0.25 MPa is an appropriate pressure for HBOT.
FAU - Zhou, J G
AU  - Zhou JG
AD  - Naval Medical Research Institute of CPLA, Shanghai 200433.
FAU - Liu, J C
AU  - Liu JC
FAU - Fang, Y Q
AU  - Fang YQ
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - China
TA  - Zhongguo Ying Yong Sheng Li Xue Za Zhi
JT  - Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = 
      Chinese journal of applied physiology
JID - 9426407
SB  - IM
MH  - Animals
MH  - *Apoptosis
MH  - Brain Ischemia/*pathology/therapy
MH  - CA1 Region, Hippocampal/*pathology
MH  - Gerbillinae
MH  - Hyperbaric Oxygenation/*methods
MH  - Neurons/*pathology
MH  - Reperfusion Injury
EDAT- 2001/02/01 00:00
MHDA- 2012/12/10 06:00
CRDT- 2010/12/22 06:00
PHST- 2010/12/22 06:00 [entrez]
PHST- 2001/02/01 00:00 [pubmed]
PHST- 2012/12/10 06:00 [medline]
PST - ppublish
SO  - Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2001 Feb;17(1):82-4.